An improved method for Y-body identification and confirmation of a high incidence of YY sperm nuclei

Human Genetics
M Klasen, M Schmid

Abstract

The fluorescence of Y-bodies and brightly fluorescing autosomal heterochromatin in quinacrine mustard stained interphase nuclei treated with distamycin A is more brilliant than in nuclei stained only with quinacrine and mustard. In the present study examinations with the aid of this method in several probands and different tissues are described. The effect of distamycin A is demonstrated to depend on its dose and the time of exposure to it. An exceptionally high frequency of YY sperm nuclei, previously also described by other studies, is confirmed in the present work. A hypothesis explaining the effect of distamycin A in interphase nuclei is discussed.

References

Jan 1, 1979·Cytogenetics and Cell Genetics·G PranteraA Rocchi
Jun 1, 1977·American Journal of Obstetrics and Gynecology·G W SalisburyJ R Lodge
Dec 23, 1977·Human Genetics·J SchlammadingerM Mikkelsen
Dec 15, 1976·Human Genetics·E SchwingerB Korte
Jan 1, 1975·Cytogenetics and Cell Genetics·M SchmidW Krone
Jan 1, 1971·Chromosoma·T C HsuB R Brinkley
Jun 6, 1970·Nature·P Barlow, C G Vosa
Jan 1, 1970·Chromosoma·T CasperssonE J Modest
Jan 1, 1972·Humangenetik·I H Pawlowitzki, P L Pearson
Jun 1, 1970·Journal of Reproduction and Fertility·P L Pearson, M Bobrow
Apr 30, 1980·Biochimica Et Biophysica Acta·C ZimmerW Guschlbauer
Jan 1, 1981·Cytogenetics and Cell Genetics·M SchmidW Engel
Jan 1, 1976·Cytogenetics and Cell Genetics·H SeuánezR V Short

❮ Previous
Next ❯

Citations

Jan 1, 1983·Human Genetics·R H MartinN L Rudd
Mar 1, 1993·Molecular Reproduction and Development·T L HanC D Matthews
Nov 1, 1986·Journal of Advanced Nursing·M J Dunlop
Jul 1, 1997·Nursing New Zealand = Kai Tiaki·T O'Connor
Jan 1, 1990·Archives of Andrology·J M Bird, J A Houghton

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.