An improved technique for isolation of environmental Vibrio cholerae with epidemic potential: monitoring the emergence of a multiple-antibiotic-resistant epidemic strain in Bangladesh

The Journal of Infectious Diseases
Shah M FaruqueJohn J Mekalanos

Abstract

Predicting cholera epidemics through monitoring the environment for the presence of pathogenic Vibrio cholerae is complicated by the presence in water of a large number of mostly nonpathogenic V. cholerae strains. V. cholerae strains causing recent cholera epidemics in Bangladesh carry the sulfamethoxazole-trimethoprim (SXT) element, which encodes resistance to several antibiotics. Here, we show that the use of a culture medium containing streptomycin, sulfamethoxazole, and trimethoprim (the antibiotic selection technique [AST]) can significantly enhance the isolation of environmental V. cholerae O1 with epidemic potential (P<.001). The AST was also used to monitor the recent emergence and spread of a new multiple-antibiotic-resistant strain of V. cholerae in Bangladesh. The results of this study support the hypothesis that pre-epidemic amplification of pathogenic V. cholerae occurs in the human host and leads to the start of an epidemic cycle dominated by a single clone of V. cholerae that spreads rapidly through environmental waters.

Citations

Aug 2, 2011·Asian Pacific Journal of Tropical Medicine·Shyamapada MandalNishith Kumar Pal
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·M KamruzzamanShah M Faruque
May 30, 2013·Proceedings of the National Academy of Sciences of the United States of America·S M Nayeemul BariShah M Faruque
Dec 2, 2009·Antimicrobial Agents and Chemotherapy·Hong Bin KimDavid C Hooper
Sep 17, 2008·Infection and Immunity·M Shamim Hasan ZahidShah M Faruque
Jan 31, 2008·Future Microbiology·Durg V Singh, Harapriya Mohapatra
May 30, 2014·Environmental Monitoring and Assessment·Subham MookerjeeAnup Palit
Jul 31, 2014·BMC Infectious Diseases·Jane-Francis Tatah Kihla Akoachere, Christelle Kwedjeu Pulcherie Mbuntcha
Aug 12, 2008·Research in Microbiology·Etinosa O Igbinosa, Anthony I Okoh
Jan 15, 2008·Journal of Microbiological Methods·Carina Lucena MendesNilma Cintra Leal
Mar 14, 2007·Research in Microbiology·Fitnat H Yildiz
Jul 4, 2012·Lancet·Jason B HarrisStephen B Calderwood
Jan 22, 2011·Journal of Medical Microbiology·Maya KitaokaStefan Pukatzki
Aug 10, 2011·Critical Reviews in Microbiology·Chandrika Murugaiah
Apr 19, 2015·BMC Infectious Diseases·Upendra Thapa ShresthaVishwanath P Agrawal
May 2, 2012·Microbes and Infection·Talena LedónRafael Fando
Jun 27, 2018·Nature Genetics·Daryl DommanNicholas R Thomson
Mar 5, 2021·Environmental Microbiology Reports·Ashish Kumar NayakBibhuti Bhusan Pal
Dec 1, 2013·Microbiology Spectrum·Salvador Almagro-Moreno, Ronald K Taylor
Oct 18, 2011·Bioorganic & Medicinal Chemistry·Megan E BolithoMartin F Semmelhack

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