PMID: 11323983Apr 28, 2001Paper

An improved three-dimensional direct numerical modelling and thermal analysis of a female breast with tumour

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
E Y Ng, N M Sudharsan

Abstract

It is well known that malignant tumour tissue generally has higher metabolic and blood perfusion rates than most normal tissues. The authors aim to show that the tissue temperature profile within the breast and the surface temperature profile can be quantified to develop an expert system or diagnostic tool for breast cancer detection. The surface temperature and tissue temperature profiles are analysed for a three-dimensional numerical model of a normal breast and a breast with a tumour. Tumours of different sizes are placed at various locations. In the model, the tissue temperature profile is distorted at the tumour location and was found to compare well with in vivo tests. It was also found that as the tumour was moved to deeper locations its effect on surface temperature was lower. It was observed that small tumours in deeper regions do not have a significant isolated impact on the surface. The numerical results could also capture a shift in the position of the tumour. For tumours greater than 10 mm in the superficial regions and of significant size in deeper regions, it could be seen that the surface temperature distribution of the breast is directly related to the position and size of the tumour embedded in it. The feasibi...Continue Reading

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Citations

Aug 26, 2006·Medical & Biological Engineering & Computing·Eddie Y K Ng, W Kee Ng
Oct 5, 2013·Medical Physics·Ravi Kumar Kannadorai, Quan Liu
Oct 16, 2015·Medical & Biological Engineering & Computing·Asnida Abd WahabKhin Wee Lai
May 26, 2017·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·R Hatwar, C Herman
Mar 22, 2018·Journal of Biomedical Optics·Geetika Dua, Ravibabu Mulaveesala
Aug 28, 2001·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·E Y Ng, N M Sudharsan
Apr 23, 2009·Journal of Medical Engineering & Technology·Q Y LinS Q Chen
Sep 17, 2009·Annals of Biomedical Engineering·Robert E Neal, Rafael V Davalos
Jul 3, 2020·Journal of Medical Systems·Aayesha Hakim, R N Awale
Dec 15, 2010·Physics in Medicine and Biology·Li JiangMurray H Loew
Feb 23, 2021·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Jaideep Dutta, Balaram Kundu
May 27, 2021·Biomedical Physics & Engineering Express·Linta AntonySeema Ansari
Aug 28, 2021·International Journal of Molecular Sciences·Thanh-Luu CaoJungwon Yoon

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