An in-house assay is superior to Sepsityper for direct matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry identification of yeast species in blood cultures

Journal of Clinical Microbiology
Marie BidartDanièle Maubon

Abstract

We developed an in-house assay for the direct identification, by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry, of yeasts in blood culture. Sixty-one representative strains from 12 species were analyzed in spiked blood cultures. Our assay accurately identified 95 of 107 (88.8%) positive blood cultures and outperformed the commercial Sepsityper kit (81.7% identification).

References

Apr 9, 2004·Journal of Clinical Microbiology·Hélène Fricker-HidalgoRenée Grillot
Jan 30, 2010·PloS One·Carine Marinach-PatriceDominique Mazier
May 12, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L FerreiraJ L Muñoz-Bellido
Mar 1, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D MartinyO Vandenberg
Apr 12, 2013·Expert Review of Proteomics·Brunella PosteraroMaurizio Sanguinetti
Oct 16, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M Puig-AsensioUNKNOWN REIPI
Feb 22, 2014·Critical Care Medicine·Mireia Puig-AsensioUNKNOWN Spanish Network for Research in Infectious Diseases

❮ Previous
Next ❯

Citations

Nov 13, 2015·Expert Review of Molecular Diagnostics·Grégory Dubourg, Didier Raoult
Feb 26, 2019·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Anne-Pauline BellangerLaurence Millon
Feb 6, 2017·Journal of Dairy Science·Juliana Regina BarreiroMarcos Veiga Dos Santos
Dec 30, 2017·Expert Review of Molecular Diagnostics·Danièle MaubonMuriel Cornet
Jan 31, 2019·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Belén Rodríguez-SánchezGilbert Greub
Oct 22, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sachio TsuchidaTomohiro Nakayama
Jan 29, 2021·Journal of Clinical Microbiology·Sean X ZhangUNKNOWN Fungal Diagnostics Laboratories Consortium (FDLC)
Jul 3, 2021·Microorganisms·Marie-Gladys RobertDanièle Maubon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.