An in vitro study on effect of Delmopinol application on Candida albicans adherence on heat cured denture base acrylic resin: a thorough study

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research
Deshraj Jain, Prabha Shakya

Abstract

Denture-related stomatitis is probably the most common form of oral candidiasis and its reported prevalence varies widely ranging up to 65%. In this thorough study, we evaluate the effect of Delmopinol application on Candida albicans adherence on heat cured denture base acrylic resin. A total of 40 specimens of heat-cured acrylic resin were made, 20 specimens were contaminated before Delmopinol treatment and 20 specimens were contaminated after Delmopinol treatment. The each specimen in each tube was individually transferred to a spectrophotometer at 530 nm wavelength in order to measure the turbidity degree, through the transmittance. Aliquots of 10 μL of each tube was then collected and inoculated into agar sabouraud plates containing 500 mMol/L of sucrose, which was incubated for 24 hours at 37°C, in order to check microbial growth. Mean of the turbidity Degree of contamination after Delmopinol application (1440.80, colony-forming unit [CFU] [×10 6 /ml]) was significantly higher than the mean of the turbidity degree of contamination before Delmopinol application (550.85 CFU [×10 6 /ml]). Heat-cured acrylic resin shows greater reduction in adherence of Candida albicans by contamination after Delmopinol application as compared...Continue Reading

Citations

Jan 13, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Julyana de Araújo OliveiraRicardo Dias de Castro
May 26, 2016·International Journal of Environmental Research and Public Health·Amal NawasrahAiman A Ali
Jun 6, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Rennan Luiz Oliveira Dos SantosClaudete Rodrigues Paula

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