An in-vivo dosimetry procedure for Elekta step and shoot IMRT

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
Savino CillaAngelo Piermattei

Abstract

The aim of this work was to extend an in-vivo dosimetry (IVD) method, previously developed by the authors for 3D-conformal radiotherapy, to step and shoot IMRT treatments for pelvic tumors delivered by Elekta linacs. The algorithm is based on correlation functions to convert EPID transit signals into in-vivo dose values at the isocenter point, Diso. The EPID images were obtained by the so-called "IMRT Dosimetric Weighting" mode as a superposition of many segment fields. This way each integral dosimetric image could be acquired in about 10 s after the end of beam delivery and could be processed while delivering the successive IMRT beams. A specific algorithm for Diso reconstruction especially featured for step and shoot IMRT was implemented using a fluence inhomogeneity index, FI, introduced to describe the degree of beam modulation with respect to open beams. A γ-analysis of 2D-EPID images obtained day to day, resulted rapid enough to verify the plan delivery reproducibility. Fifty clinical IMRT beams, planned for patients undergoing radiotherapy of pelvic tumors, were used to irradiate a homogeneous phantom. For each beam the agreement between the reconstructed dose, Diso, and the TPS computed dose, Diso,TPS, was well within 5...Continue Reading

References

Jun 3, 1998·Medical Physics·D A LowJ A Purdy
Aug 12, 1999·Physics in Medicine and Biology·J M KapatoesT R Mackie
Dec 29, 1999·International Journal of Radiation Oncology, Biology, Physics·K L PasmaB J Heijmen
Aug 15, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Tom DepuydtDominique Pierre Huyskens
Oct 19, 2004·Medical Physics·Hugo Bouchard, Jan Seuntjens
Jun 22, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Francisco Sánchez-DobladoGünther H Hartmann
Nov 11, 2005·Medical Physics·Peter WinklerDietmar Georg
Feb 9, 2006·Radiation Protection Dosimetry·J Van DamA Wambersie
Apr 11, 2006·Radiation Protection Dosimetry·Simon Greene, Robert A Price
Mar 31, 2007·International Journal of Radiation Oncology, Biology, Physics·Leah N McDermottBen J Mijnheer
Jun 15, 2007·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·S CillaA Piermattei
Aug 3, 2007·Physics in Medicine and Biology·Angelo PiermatteiAlessio G Morganti
Nov 8, 2007·Medical Physics·S M J J G NijstenA W H Minken
Mar 20, 2008·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Angelo PiermatteiAlessio Morganti
Aug 19, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Wouter van ElmptBen Mijnheer
Sep 4, 2008·Radiation Protection Dosimetry·Ben Mijnheer
Jul 21, 2009·Medical Physics·Angelo PiermatteiVincenzo Fusco
Feb 9, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Björn PoppeKay C Willborn
Mar 5, 2010·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Andrea FidanzioAngelo Piermattei
Mar 17, 2010·Medical Physics·Andrea L McNivenThomas G Purdie
Jul 10, 2010·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Pascal FrancoisAlejandro Mazal
Jul 17, 2010·Medical Physics·A MansJ C Stroom
Jan 11, 2011·Technology in Cancer Research & Treatment·S CillaA Piermattei
Jul 26, 2011·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·J RichartM Santos
Jun 22, 2013·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Guang-hua JinXiao-wei Liu
Jul 5, 2013·Medical Physics·Ben MijnheerChester Reft

❮ Previous
Next ❯

Citations

Jun 1, 2014·Medical Physics·A FidanzioA Piermattei
Nov 18, 2015·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Jérémy CamilleriXavier Franceries
Oct 30, 2015·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Savino CillaAngelo Piermattei
May 3, 2016·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·K RickettsA Adeyemi
Jun 7, 2017·Technology in Cancer Research & Treatment·Stefano PecaWendy Lani Smith
Jun 7, 2018·Technology in Cancer Research & Treatment·Maria D FalcoAngelo Piermattei
Nov 15, 2017·Medical Physics·Olivier PisaturoAbdelkarim Said Allal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.