An Incidental Finding of Choroidal Ganglioneuronal Hamartoma in a Patient With Neurofibromatosis Type 1

Ophthalmic Plastic and Reconstructive Surgery
Ingrid ChangJing Zhang


A 42-year-old man with neurofibromatosis type 1 underwent a giant facial neurofibroma resection and enucleation of the right eye. He was found to have a diffusely thickened and cellular choroid containing individual or small clusters of large ganglion and medium-sized neuronal cells. The nomenclature of this lesion is difficult; however, the term choroidal ganglioneuronal hamartoma has been favored due to the lack of proliferative activity and diffuse nature of the lesion arguing against a neoplastic etiology. This case highlights an interesting presentation of neurofibromatosis type I.


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Jan 1, 1983·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·J J WoogD Horns
Dec 1, 1983·Ophthalmology·S Brownstein, J M Little
Jul 1, 1994·Journal of Neurosurgery·G B WellsE L Zager
Mar 10, 2010·Archives of Ophthalmology·Suryasnata RathGeeta K Vemuganti
May 17, 2011·European Journal of Ophthalmology·Kan IshijimaSusumu Ishida
Oct 10, 2012·Archives of Ophthalmology·Eleonora M LadPeter R Egbert
Sep 5, 2014·Ophthalmic Plastic and Reconstructive Surgery·Sunali GoyalJohn D Pemberton

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