An Incidental Finding of Choroidal Ganglioneuronal Hamartoma in a Patient With Neurofibromatosis Type 1

Ophthalmic Plastic and Reconstructive Surgery
Ingrid ChangJing Zhang

Abstract

A 42-year-old man with neurofibromatosis type 1 underwent a giant facial neurofibroma resection and enucleation of the right eye. He was found to have a diffusely thickened and cellular choroid containing individual or small clusters of large ganglion and medium-sized neuronal cells. The nomenclature of this lesion is difficult; however, the term choroidal ganglioneuronal hamartoma has been favored due to the lack of proliferative activity and diffuse nature of the lesion arguing against a neoplastic etiology. This case highlights an interesting presentation of neurofibromatosis type I.

References

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Mar 10, 2010·Archives of Ophthalmology·Suryasnata RathGeeta K Vemuganti
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Oct 10, 2012·Archives of Ophthalmology·Eleonora M LadPeter R Egbert
Sep 5, 2014·Ophthalmic Plastic and Reconstructive Surgery·Sunali GoyalJohn D Pemberton

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Citations

Mar 13, 2016·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Marwah M AbdulkaderJose M Bonnin
Nov 20, 2018·Journal of Pediatric Ophthalmology and Strabismus·Ahmed Gilani, Amanda Treece
May 27, 2020·Journal of Ophthalmology·Zhaoxin JiangXiaoyan Ding
Dec 15, 2020·BMC Ophthalmology·Zhaoxin JiangXiaoyan Ding

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