An independent dose calculation algorithm for MLC-based radiotherapy including the spatial dependence of MLC transmission

Physics in Medicine and Biology
Friedlieb LorenzPiotr Zygmanski

Abstract

An analytical dose calculation algorithm was developed and commissioned to calculate dose delivered with both static and dynamic multileaf collimator (MLC) in a homogenous phantom. The algorithm is general; however, it was designed specifically to accurately model dose for large and complex IMRT fields. For such fields the delivered dose may have a considerable contribution from MLC transmission, which is dependent upon spatial considerations. Specifically, the algorithm models different MLC effects, such as interleaf transmission, the tongue-and-groove effect, rounded leaf ends, MLC scatter, beam hardening and divergence of the beam, which results in a gradual MLC transmission fall-off with increasing off-axis distance. The calculated dose distributions were compared to measured dose using different methods (film, ionization chamber array, single ionization chamber), and the differences among the treatment planning system, the measurements and the developed algorithm were analysed for static MLC and dynamic IMRT fields. It was found that the calculated dose from the developed algorithm agrees very well with the measurements (mostly within 1.5%) and that a constant value for MLC transmission is insufficient to accurately predic...Continue Reading

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Jun 9, 2007·Medical Physics·Friedlieb LorenzPiotr Zygmanski

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Citations

Mar 23, 2013·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·P TsiamasP Zygmanski
Jul 23, 2011·Medical Physics·P TsiamasP Zygmanski
Mar 10, 2010·Zeitschrift für medizinische Physik·Friedlieb LorenzPiotr Zygmanski
Aug 13, 2010·Physics in Medicine and Biology·Mandar S BhagwatPiotr Zygmanski
Sep 17, 2010·Physics in Medicine and Biology·Mandar S BhagwatPiotr Zygmanski
Nov 18, 2010·Physics in Medicine and Biology·Weiguo Lu
Jun 22, 2019·Journal of Applied Clinical Medical Physics·Laure VieillevigneVictor Hernandez
Jul 18, 2015·Physics in Medicine and Biology·Lukas GoertzPiotr Zygmanski
Dec 14, 2018·Physics in Medicine and Biology·Victor HernandezJordi Saez
Nov 28, 2015·Physics in Medicine and Biology·Juan Diego AzconaJavier Burguete
Mar 7, 2021·Journal of Applied Clinical Medical Physics·Friedlieb H Lorenz, Matthew I Paris

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