An Individually Optimized Protocol of Contrast Medium Injection in Enhanced CT Scan for Liver Imaging

Contrast Media & Molecular Imaging
Shi-Ting FengZi-Ping Li

Abstract

To investigate the effectiveness of a new individualized contrast medium injection protocol for enhanced liver CT scan. 324 patients who underwent plain and dual phase enhanced liver CT were randomly assigned to 2 groups: G1 (n = 224, individualized contrast medium injection protocol); G2 (n = 100, standard contrast medium injection with a dose of 1.5 ml/kg). CT values and ΔHU (CT values difference between plain and enhanced CT) of liver parenchyma and tumor-liver contrast (TLC) during hepatic arterial phase (HAP) and portal venous phase (PVP) and contrast medium dose were measured. The tumor conspicuity of hepatocellular carcinoma (HCC) between two groups was independently evaluated by two radiologists. The mean contrast medium dose of G1 was statistically lower than that of G2. There were no significantly statistical differences in CT values and ΔHU of liver parenchyma during HAP, TLC values during HAP, and PVP between two groups. The CT values and ΔHU of liver parenchyma during PVP of G2 were significantly higher than those of G1. Two independent radiologists were both in substantial conformity in grading tumor conspicuity. Using the individually optimized injection protocol might reduce contrast medium dose without impactin...Continue Reading

References

Aug 1, 1989·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·H SvanholmS Olsen
Aug 1, 1994·AJR. American Journal of Roentgenology·R L Baron
Feb 24, 2001·Journal of Vascular and Interventional Radiology : JVIR·M M Waybill, P N Waybill
Mar 21, 2003·AJR. American Journal of Roentgenology·Paul J DorioSarah A Shock
Apr 6, 2004·The Surgical Clinics of North America·John E SkandalakisPetros Mirilas
Nov 3, 2004·Journal of the American College of Cardiology·Giancarlo MarenziAntonio L Bartorelli
Aug 1, 2007·World Journal of Gastroenterology : WJG·Rong TuLing Wu
Nov 17, 2007·Investigative Radiology·Dushyant V SahaniUNKNOWN Investigators of the IMPACT Study
Mar 14, 2008·European Journal of Radiology·Estanislao AranaConsuelo Sierra
Mar 22, 2008·AJR. American Journal of Roentgenology·Yumi YanagaYasuyuki Yamashita
Jul 24, 2010·European Journal of Radiology·Yusuke TsugeKyongtae T Bae
Feb 7, 2012·European Journal of Radiology·Tetsuya FujigaiTakamichi Murakami

❮ Previous
Next ❯

Software Mentioned

P3T
SPSS
Vitrea
[UNK]

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.