An inhomogeneity correction algorithm for irregular fields of high-energy photon beams based on Clarkson integration and the 3D beam subtraction method

Journal of Applied Clinical Medical Physics
Sotirios StathakisJ C Rosenwald

Abstract

A number of treatment-planning systems still use conventional correction methods for body inhomogeneities. Most of these methods (power law method, tissue-air ratio (TAR), etc.) consider only on-axis points, rectangular fields, and inhomogeneous slabs covering the whole irradiating field. A new method is proposed that overcomes the above limitations. The new method uses the principle of the Clarkson method on sector integration to take into account the position and lateral extent of the inhomogeneity with respect to the point of calculation, as well as the shape of the irradiating field. The field is divided into angular sectors, and each sector is then treated separately for the presence of inhomogeneities using a conventional correction method. Applying this method, we can predict the correction factors for Co-60 and 6-MV photon beams for irregular fields that include inhomogeneities of lower or higher densities relative to water. Validation of the predicted corrections factors was made against Monte Carlo calculations for the same geometries. The agreement between the predicted correction factors and the Monte Carlo calculations was within 1.5%. In addition, the new method was able to predict the behavior of the correction f...Continue Reading

References

Sep 1, 1990·Medical Physics·J W Wong, J A Purdy
Mar 1, 1986·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·K Kappas, J C Rosenwald
May 1, 1984·Medical Physics·E El-Khatib, J J Battista
May 1, 1995·Medical Physics·D W RogersT R Mackie
Jun 15, 1995·International Journal of Radiation Oncology, Biology, Physics·C Kappas, J C Rosenwald
Dec 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A KosunenA Väänänen
Jan 15, 1996·International Journal of Radiation Oncology, Biology, Physics·E YorkeR Altemus
Aug 22, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M EngelsmanB J Mijnheer
Apr 1, 1957·Physics in Medicine and Biology·J E O'CONNOR

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Citations

Nov 26, 2009·Medical Physics·Niko Papanikolaou, Sotirios Stathakis
Sep 3, 2008·The British Journal of Radiology·S KimA Saleem
Oct 22, 2013·Radiation Oncology·Hee Jung KimSung-Joon Ye
Aug 22, 2009·AJR. American Journal of Roentgenology·Hyun Jin ParkJung Suk Oh
Mar 14, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James M Galvin, Wilfried De Neve
Nov 26, 2019·Journal of Applied Clinical Medical Physics·Andries N SchreuderJohn B Wilkinson

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Methods Mentioned

BETA
irradiating
irradiate

Software Mentioned

PEREGRINE
PLATO
DOSXYZ
ETAR
Batho

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