An Initial Study of Alexithymia and Its Relationship With Cognitive Abilities Among Mild Cognitive Impairment, Mild Alzheimer's Disease, and Healthy Volunteers

The Journal of Nervous and Mental Disease
Daniela SmirniSergio Paradiso

Abstract

The present study examined the degree to which alexithymia is greater in mild Alzheimer's disease (AD) and mild cognitive impairment (MCI) relative to healthy volunteers (healthy comparison [HC]), and investigated relationships between alexithymia and cognition. Eighty-five participants (MCI = 30, AD = 21, HC = 34) underwent a comprehensive neuropsychological examination and completed the 20-item Toronto Alexithymia Scale (TAS-20). Relative to HC, MCI and AD reported greater alexithymia total scores and higher scores on the TAS factor difficulty in identifying feelings (DIF). The remaining two factors, difficulty in describing feelings (DDF) and externally oriented thinking showed no significant group differences. In MCI, TAS-20 and DIF were negatively correlated with working and long-term verbal memory. In AD, TAS-20 was negatively correlated with general cognition, attention, memory, and visual spatial constructive and executive abilities. Also in AD, DIF was negatively correlated with general cognition, memory, and executive abilities. The correlation between DIF and long-term verbal memory in both MCI and AD suggests a potential common mechanism for alexithymia in these neurocognitive disorders. Declines in verbal memory ma...Continue Reading

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Citations

Oct 5, 2019·Behavioural Neurology·Francesca Felicia OpertoMichele Roccella
Apr 2, 2019·The Journal of Nervous and Mental Disease·Daniela SmirniMarco Carotenuto
Jan 27, 2021·Brain Sciences·Ariela Gigi, Merav Papirovitz
Dec 31, 2020·Journal of Clinical Medicine·Eva Mª Arroyo-AnllóRoger Gil

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