PMID: 15348447Sep 7, 2004Paper

An innovative auto-catalytic deposition route to produce calcium-phosphate coatings on polymeric biomaterials

Journal of Materials Science. Materials in Medicine
I B Leonor, R L Reis

Abstract

The aim of this research is to develop a new methodology to obtain bioactive coatings on bioinert and biodegradable polymers that are not intrinsically bioactive. In this study three types of materials were used as substrates: (i) high molecular weight polyethylene (HMWPE) and two different types of starch based blends (ii) starch/ethylene vinyl alcohol blends, SEVA-C and (iii) starch/cellulose acetate blends, SCA. Two types of baths were originally proposed and studied to produce novel auto-catalytic calcium-phosphate (Ca-P) coatings. Then, the coated surfaces were analyzed by scanning electron microscopy and energy dispersive spectroscopy (SEM/EDS), as produced, and after different immersion periods in SBF. The evolution of Ca and P concentrations was determined by induced-coupled plasma emission (ICP) spectroscopy. The crystalline phases present on the films formed on the different material surfaces, after a certain soaking time, were identified by thin-film X-ray diffraction (TF-XRD). The obtained results indicated that it was possible to coat the materials surfaces with a Ca-P layer with only 60 min of immersion in both types of auto-catalytic solutions. Furthermore, it was possible to observe the clear bioactive nature of...Continue Reading

Citations

Mar 12, 2005·Journal of Biomedical Materials Research. Part a·G A SilvaR L Reis
Jan 9, 2008·Journal of Tissue Engineering and Regenerative Medicine·I B LeonorT Nakamura
Oct 27, 2007·Journal of Biomaterials Science. Polymer Edition·Jan ChłopekDaniel Sabat
Dec 18, 2012·Journal of Materials Science. Materials in Medicine·Charlie R CampionKarin A Hing
Apr 6, 2007·Journal of Materials Science. Materials in Medicine·Jin-Ming WuAkiyoshi Osaka

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