An Insight into the Changes in Skin Texture and Properties following Dietary Intervention with a Nutricosmeceutical Containing a Blend of Collagen Bioactive Peptides and Antioxidants

Skin Pharmacology and Physiology
Licia GenoveseSara Sibilla

Abstract

Skin aging is a multifactorial phenomenon which causes alterations in skin physiological functions and, most visibly, phenotypic changes. In particular, during the aging process, hyaluronic acid, collagen, and elastin fibers undergo structural and functional changes. This study aimed to give an insight into the photo-protective benefits and efficacy of an oral liquid nutricosmeceutical containing collagen bioactive peptides and antioxidants to counteract the signs of aging. A double-blind, randomized, placebo-controlled clinical trial was conducted by an independent esthetic clinic on 120 healthy volunteer subjects for 90 days. Subjects were divided into 2 groups: 60 subjects consumed 1 bottle (50 mL) of the nutricosmeceutical daily and the other 60 consumed 1 bottle (50 mL) of the placebo. Outcome measures were related to skin elasticity (expressed as Young's elasticity modulus) and skin architecture (histological analysis). In addition, the subjects recruited in this study underwent observational assessments through self-assessment questionnaires. Overall, we demonstrated a significant increase in skin elasticity (+7.5%), p ≤ 0.001 and an improvement in skin texture after daily oral consumption of the nutricosmeceutical. We a...Continue Reading

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Citations

Aug 15, 2019·Journal of Cosmetic Dermatology·Nikita JhawarNazanin Saedi
Jun 9, 2020·Experimental and Therapeutic Medicine·Mihaela-Adi LupuCristiana Tanase
May 22, 2020·Journal of Cosmetic Dermatology·Meisam BaratiSayed Hossein Davoodi
Feb 27, 2020·Antioxidants·Gabriel Aguirre-CruzGabriel Aguirre-Álvarez
Mar 21, 2021·International Journal of Dermatology·Roseane B de MirandaRochele C Rossi
Jun 3, 2021·Cells·Gabriela Rapozo GuimarãesMariana Boroni
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Patrícia Maria Berardo Gonçalves Maia CamposElodie Bouvret
Oct 26, 2021·Journal of Cosmetic Dermatology·Andrea M RustadPeter A Lio

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