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An integrative functional genomics framework for effective identification of novel regulatory variants in genome-phenome studies

Genome Medicine

Jan 29, 2018

Junfei ZhaoZhong-Ming Zhao

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Abstract

Genome-phenome studies have identified thousands of variants that are statistically associated with disease or traits; however, their functional roles are largely unclear. A comprehensive investigation of regulatory mechanisms and the gene regulatory networks between phenome-wide associ...read more

Mentioned in this Paper

Enhancer brand
Gene Expression
CSF3 gene
Mental Retardation
Quantitative Trait Loci
Asthma
Study
Functional Genomics
Gene Mutant
Single Nucleotide Polymorphism
14
48
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An integrative functional genomics framework for effective identification of novel regulatory variants in genome-phenome studies

Genome Medicine

Jan 29, 2018

Junfei ZhaoZhong-Ming Zhao

PMID: 29378629

DOI: 10.1186/s13073-018-0513-x

Abstract

Genome-phenome studies have identified thousands of variants that are statistically associated with disease or traits; however, their functional roles are largely unclear. A comprehensive investigation of regulatory mechanisms and the gene regulatory networks between phenome-wide associ...read more

Mentioned in this Paper

Enhancer brand
Gene Expression
CSF3 gene
Mental Retardation
Quantitative Trait Loci
14
48

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References77
  • Citations1
12345...

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