PMID: 11219746Feb 24, 2001

An intelligent rapid odour recognition model in discrimination of Helicobacter pylori and other gastroesophageal isolates in vitro

Biosensors & Bioelectronics
A K PavlouA P Turner

Abstract

Two series of experiments are reported which result in the discrimination between Helicobacter pylori and other bacterial gastroesophageal isolates using a newly developed odour generating system, an electronic nose and a hybrid intelligent odour recognition system. In the first series of experiments, after 5 h of growth (37 degrees C), 53 volatile 'sniffs' were collected over the headspace of complex broth cultures of the following clinical isolates: Staphylococcus aureus, Klebsiella sp., H. pylori, Enterococcus faecalis (10(7) ml(-1)), Mixed infection (Proteus mirabilis, Escherichia coli, and E. faecalis 3 x 10(6) ml each) and sterile cultures. Fifty-six normalised variables were extracted from 14 conductive polymer sensor responses and analysed by a 3-layer back propagation neural network (NN). The NN prediction rate achieved was 98% and the test data (37.7% of all data) was recognised correctly. Successful clustering of bacterial classes was also achieved by discriminant analysis (DA) of a normalised subset of sensor data. Cross-validation identified correctly seven 'unknown' samples. In the second series of experiments after 150 min of microaerobic growth at 37 degrees C, 24 volatile samples were collected over the headspa...Continue Reading

References

Apr 1, 1978·Journal of Clinical Pathology·P J Coloe
Mar 1, 1976·Postgraduate Medical Journal·K Liddell
Jul 1, 1973·International Journal of Dermatology·I H Distelheim, A Dravnieks
Dec 25, 1982·Lancet·M SmithB Levinson
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·F Mégraud
Jan 15, 1996·Analytical Chemistry·R Goodacre, D B Kell
Jan 1, 1997·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·J ChunM Goodfellow
Dec 9, 1997·Journal of Clinical Pathology·S ChandiokK C Persaud
Jan 1, 1997·Biosensors & Bioelectronics·P WangF Shen
Jul 4, 1998·Trends in Biotechnology·T A DickinsonDavid R Walt
Apr 28, 1999·IEEE Transactions on Bio-medical Engineering·B G KermaniH T Nagle

Citations

Sep 24, 2002·Biosensors & Bioelectronics·A K PavlouA P Turner
Jul 2, 2003·Biosensors & Bioelectronics·Corrado Di NataleArnaldo D'Amico
Nov 5, 2002·Current Opinion in Chemical Biology·David R Walt
Jun 4, 2010·The Journal of Laryngology and Otology·N CharakliasC A Kendall
Mar 26, 2004·Nature Reviews. Microbiology·A P Turner, N Magan
Oct 23, 2002·Letters in Applied Microbiology·A K PavlouN Magan
Jul 8, 2011·Clinical Microbiology Reviews·Trevor Winstanley, Patrice Courvalin
Nov 10, 2005·International Journal of Neural Systems·Vassilis S Kodogiannis, Edmund Wadge
Mar 8, 2005·American Journal of Respiratory and Critical Care Medicine·Roberto F MachadoSerpil C Erzurum
Nov 20, 2009·American Journal of Respiratory and Critical Care Medicine·Roberto F Machado
Feb 22, 2012·Sensors·Alphus D Wilson, Manuela Baietto
Feb 16, 2011·Biomedical Chromatography : BMC·Agnieszka UlanowskaBogusław Buszewski
Nov 13, 2008·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Vassilis S KodogiannisHardial S Chowdrey
Jan 18, 2006·Letters in Applied Microbiology·I A CasalinuovoM Coletta
Jun 25, 2005·Computer Methods and Programs in Biomedicine·J W T YatesL Beeby
Jan 28, 2014·Journal of Laboratory Automation·Andrew O Fung, Natalia Mykhaylova
Jan 1, 2009·Sensors·Alphus D Wilson, Manuela Baietto
Sep 28, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·S ChatterjeeJ F Feller

Related Concepts

Esophagus
Odors
Stomach
Helicobacter pylori
Neural Network Simulation

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.