PMID: 11219746Feb 24, 2001

An intelligent rapid odour recognition model in discrimination of Helicobacter pylori and other gastroesophageal isolates in vitro

Biosensors & Bioelectronics
A K PavlouA P Turner


Two series of experiments are reported which result in the discrimination between Helicobacter pylori and other bacterial gastroesophageal isolates using a newly developed odour generating system, an electronic nose and a hybrid intelligent odour recognition system. In the first series of experiments, after 5 h of growth (37 degrees C), 53 volatile 'sniffs' were collected over the headspace of complex broth cultures of the following clinical isolates: Staphylococcus aureus, Klebsiella sp., H. pylori, Enterococcus faecalis (10(7) ml(-1)), Mixed infection (Proteus mirabilis, Escherichia coli, and E. faecalis 3 x 10(6) ml each) and sterile cultures. Fifty-six normalised variables were extracted from 14 conductive polymer sensor responses and analysed by a 3-layer back propagation neural network (NN). The NN prediction rate achieved was 98% and the test data (37.7% of all data) was recognised correctly. Successful clustering of bacterial classes was also achieved by discriminant analysis (DA) of a normalised subset of sensor data. Cross-validation identified correctly seven 'unknown' samples. In the second series of experiments after 150 min of microaerobic growth at 37 degrees C, 24 volatile samples were collected over the headspa...Continue Reading


Apr 1, 1978·Journal of Clinical Pathology·P J Coloe
Mar 1, 1976·Postgraduate Medical Journal·K Liddell
Jul 1, 1973·International Journal of Dermatology·I H Distelheim, A Dravnieks
Dec 25, 1982·Lancet·M SmithB Levinson
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·F Mégraud
Jan 15, 1996·Analytical Chemistry·R Goodacre, D B Kell
Jan 1, 1997·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·J ChunM Goodfellow
Dec 9, 1997·Journal of Clinical Pathology·S ChandiokK C Persaud
Jan 1, 1997·Biosensors & Bioelectronics·P WangF Shen
Jul 4, 1998·Trends in Biotechnology·T A DickinsonDavid R Walt
Apr 28, 1999·IEEE Transactions on Bio-medical Engineering·B G KermaniH T Nagle


Sep 24, 2002·Biosensors & Bioelectronics·A K PavlouA P Turner
Jul 2, 2003·Biosensors & Bioelectronics·Corrado Di NataleArnaldo D'Amico
Nov 5, 2002·Current Opinion in Chemical Biology·David R Walt
Jun 4, 2010·The Journal of Laryngology and Otology·N CharakliasC A Kendall
Mar 26, 2004·Nature Reviews. Microbiology·A P Turner, N Magan
Oct 23, 2002·Letters in Applied Microbiology·A K PavlouN Magan
Jul 8, 2011·Clinical Microbiology Reviews·Trevor Winstanley, Patrice Courvalin
Nov 10, 2005·International Journal of Neural Systems·Vassilis S Kodogiannis, Edmund Wadge
Mar 8, 2005·American Journal of Respiratory and Critical Care Medicine·Roberto F MachadoSerpil C Erzurum
Nov 20, 2009·American Journal of Respiratory and Critical Care Medicine·Roberto F Machado
Feb 22, 2012·Sensors·Alphus D Wilson, Manuela Baietto
Feb 16, 2011·Biomedical Chromatography : BMC·Agnieszka UlanowskaBogusław Buszewski
Nov 13, 2008·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Vassilis S KodogiannisHardial S Chowdrey
Jan 18, 2006·Letters in Applied Microbiology·I A CasalinuovoM Coletta
Jun 25, 2005·Computer Methods and Programs in Biomedicine·J W T YatesL Beeby
Jan 28, 2014·Journal of Laboratory Automation·Andrew O Fung, Natalia Mykhaylova
Jan 1, 2009·Sensors·Alphus D Wilson, Manuela Baietto
Sep 28, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·S ChatterjeeJ F Feller

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