An interhemispheric asymmetry in motor cortex disinhibition during bimanual movement

Brain Research
James W Stinear, Winston D Byblow

Abstract

The release of short interval intracortical inhibition (SICI) induced by passive bimanual movement was assessed in dominant and non-dominant primary motor cortices (M1). Dual-pulse focal transcranial magnetic stimulation (TMS) was delivered over M1 while the limbs were at rest, and during the mid-flexion phase of contralateral rhythmical wrist flexion-extension. Test and conditioned responses were recorded from flexor carpi radialis (FCR) when the wrist was passively moving alone, during bimanual mirror symmetric passive synchronous movement, and during bimanual passive asynchronous movement. Tonic inhibition was released to a greater extent in the non-dominant M1 than in the dominant M1 during synchronous mirror symmetric movement. This interhemispheric asymmetry was not evident during asynchronous movement. The findings support the idea that the dominant M1 has the capacity to disinhibit homologous representations in the contralateral M1 during synchronous movement, but the non-dominant M1 does not reciprocate to the same extent.

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Citations

Aug 17, 2010·Experimental Brain Research·Alison L Smith, W Richard Staines
May 21, 2005·Brain Research. Brain Research Reviews·R G Carson
Jul 30, 2010·Journal of Neurophysiology·Juliette A Yedimenko, Monica A Perez
Jan 29, 2011·Journal of Neurophysiology·Demetris S Soteropoulos, Monica A Perez
Jun 14, 2013·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Na Jin Seo
Oct 16, 2015·Experimental Brain Research·Deanna M KennedyCharles H Shea
Mar 17, 2012·Archives of Physical Medicine and Rehabilitation·Jacqui H Morris, Frederike Van Wijck
Jan 10, 2014·Somatosensory & Motor Research·Abbas OrandShigeru Sonoda
Dec 23, 2014·Behavioural Brain Research·Charles T LeonardMarlesa Moore
Dec 28, 2016·Human Movement Science·Deanna M KennedyCharles H Shea
Jan 9, 2018·Cerebral Cortex·Florent LebonCharalambos Papaxanthis
Mar 22, 2008·Brain : a Journal of Neurology·Cathy M StinearWinston D Byblow
Jan 17, 2017·Experimental Brain Research·David A CunninghamEla B Plow
Apr 18, 2018·Experimental Brain Research·Wan-Wen LiaoSandy McCombe Waller
Oct 28, 2019·Experimental Brain Research·Deanna M KennedyCharles H Shea
Dec 17, 2014·Physiological Reports·Nimeshan GeevasingaSteve Vucic
May 29, 2018·Journal of the Neurological Sciences·Anna Paula ChagasKátia Monte-Silva

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