An international collaborative study of 105 new cases of adenomatoid odontogenic tumors.

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Ana Luiza Oliveira Corrêa RozaPablo Agustin Vargas

Abstract

The aim of this study was to report the clinicopathologic features of 105 new cases of adenomatoid odontogenic tumor (AOT) from Brazil, Guatemala, Mexico, and South Africa. Clinical and radiographic data were collected from records of 5 oral pathology laboratories, and all cases were microscopically reviewed. This series of cases included 36 (34.2%) from South Africa; 33 (31.4%) from Brazil; 23 (21.9%) from Mexico; and 13 (12.3%) from Guatemala. Seventy-two patients (68.5%) were females and 33 patients (31.4%) were males, with an average age of 19.2 years. The tumors predominantly affected the anterior maxilla (48.5%), followed by the anterior mandible (29.5%); posterior mandible (15.2%); and posterior maxilla (6.6%). Sixty-three tumors (63.6%) were follicular, 34 (34.3%) were extrafollicular, and 2 (2%) were peripheral. In most cases, the tumors caused considerable cortical expansion (average size 3.4 cm). Microscopically, most cases showed rosette-like and duct-like structures. This is one of the largest case series of AOTs reported in the literature and the first multicenter study involving populations from Latin America and South Africa. In a fifth of the present cases, the posterior regions of the gnathic bones were affect...Continue Reading

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Sep 30, 2020·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Ana Luiza Oliveira Corrêa RozaPablo Agustin Vargas

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