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An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells

bioRxiv

Nov 18, 2013

David Andrew TurnerAlfonso Martinez Arias

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Abstract

Embryonic Stem cells derived from the epiblast tissue of the mammalian blastocyst retain the capability to differentiate into any adult cell type and are able to self-renew indefinitely under appropriate culture conditions. Despite the large amount of knowledge that we have accumulated ...read more

Mentioned in this Paper

Embryo Stage 3 Structure
Blastocyst Structure
NODAL gene
Wnt Signaling Pathway
Adult Stem Cells
Bone morphogenetic protein 4
Activins
Entire Blastocyst
Extracellular
Cell Fate
14
9
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  • An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells

    bioRxiv

    Nov 18, 2013

    David Andrew TurnerAlfonso Martinez Arias

    PMID: 990000653

    DOI: 10.1101/000653

    Abstract

    Embryonic Stem cells derived from the epiblast tissue of the mammalian blastocyst retain the capability to differentiate into any adult cell type and are able to self-renew indefinitely under appropriate culture conditions. Despite the large amount of knowledge that we have accumulated ...read more

    Mentioned in this Paper

    Embryo Stage 3 Structure
    Blastocyst Structure
    NODAL gene
    Wnt Signaling Pathway
    Adult Stem Cells
    14
    9

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