An intervention to improve spontaneous adverse drug reaction reporting by hospital physicians: a time series analysis in Spain

Drug Safety : an International Journal of Medical Toxicology and Drug Experience
Consuelo PedrósJosep Maria Arnau

Abstract

Spontaneous reporting of adverse drug reactions (ADRs) in hospitals is scarce and several obstacles to such reporting have been identified previously. To assess the effectiveness of a multifaceted intervention based on healthcare management agreements for improving spontaneous reporting of ADRs by physicians in a hospital setting. In 2003, the spontaneous reporting of ADRs was included as one of the objectives of hospital physicians at the Vall d'Hebron Hospital, Barcelona, Spain, within the context of management agreements between clinical services and hospital managers. A continuous intervention related to these management agreements, including periodic educational meetings and economic incentives, was then initiated. We carried out an ecological time series analysis and assessed the change in the total number of spontaneous reports of ADRs, and the number of serious ADRs, unexpected ADRs, and ADRs associated with new drugs between a period previous to the intervention (from 1998 to 2002) and the period during the intervention (from 2003 to 2005). A time series analysis with ARIMA (Auto-Regressive Integrated Moving Average) models was performed. The median number of reported ADRs per year increased from 40 (range 23-55) in th...Continue Reading

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Citations

Jun 17, 2010·European Journal of Clinical Pharmacology·Gloria CerezaJosep Maria Arnau
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Aug 25, 2010·BMC Health Services Research·Pieter Van HerckWalter Sermeus
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Related Concepts

Education, Medical, Continuing
Hospitals
Prescribing Patterns, Physician
Physicians
Pay for Performance
Adverse Drug Reaction Reporting Systems
Attending Physicians, Hospital
Regression Analysis
Adverse Reaction to Drug
Health Care

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