An inventory of concerns behind blood safety policies in five Western countries

Transfusion
Koen KramerHans L Zaaijer

Abstract

The availability of costly safety measures against transfusion-transmissible infections forces Western countries to confront difficult ethical questions. How to decide about implementing such measures? When are such decisions justified? As a preliminary to addressing these questions, we assessed which concerns shape actual donor blood safety policymaking in five Western countries. Our qualitative study involved determining which issues had been discussed in advisory committee meetings and capturing these issues in general categories. Appropriate documents were identified in collaboration with local decision-making experts in Canada, Germany, the Netherlands, the United States, and the United Kingdom. The introduction of hepatitis B virus nucleic acid testing and selected measures against variant Creutzfeldt-Jakob disease, West Nile virus, and Q-fever were chosen as cases representing decision-making on safety measures with high costs and low or uncertain added safety. A broad inventory of concerns was established, including: 1) nine categories of advantages and disadvantages of candidate safety policies; 2) six kinds of difficulties in assessing risks and forecasting the effects of safety policies; 3) 13 decision-making princip...Continue Reading

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Citations

Jan 20, 2016·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·B Pozzetto, O Garraud
Jan 16, 2016·Transfusion·Judie Leach Bennett
Feb 17, 2017·The American Journal of Bioethics : AJOB·Cristian Timmermann
Feb 13, 2016·Journal of Medical Ethics·Marcel Verweij, Koen Kramer
Sep 21, 2018·Vox Sanguinis·Judie Leach Bennett, Dana V Devine
Jan 20, 2018·Journal of Risk Research·Kumanan WilsonJennifer Keelan

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