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An investigation into the hepatic cytochrome P-450 catalysed metabolism of the anaesthetic fluroxene (2,2,2-trifluoroethyl vinyl ether)

The South African Journal of Medical Sciences

Jan 1, 1975

Julie A MarshLaurence S Kaminsky

PMID: 1863

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Abstract

The role of the different cytochromes P-450 in the metabolism of the anaesthetic agent fluroxene, and the mechanism of production of toxic effects seen after pre-treatment of the animals with pehnobarbital prior to anaesthesia, have been investigated. Male rats were anaesthetized with f...read more

Mentioned in this Paper

Ethers
Enzyme Induction
Luminal
Cytochrome P-450 Oxygenase
Cytochromes
Ethyl ether
Allylisopropylacetamide
Methylcholanthrene
Liver
Microsomes, Liver
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  • An investigation into the hepatic cytochrome P-450 catalysed metabolism of the anaesthetic fluroxene (2,2,2-trifluoroethyl vinyl ether)

    The South African Journal of Medical Sciences

    Jan 1, 1975

    Julie A MarshLaurence S Kaminsky

    PMID: 1863

    DOI:

    Abstract

    The role of the different cytochromes P-450 in the metabolism of the anaesthetic agent fluroxene, and the mechanism of production of toxic effects seen after pre-treatment of the animals with pehnobarbital prior to anaesthesia, have been investigated. Male rats were anaesthetized with f...read more

    Mentioned in this Paper

    Ethers
    Enzyme Induction
    Luminal
    Cytochrome P-450 Oxygenase
    Cytochromes

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