An investigation of the conformational and self-aggregational processes of histones using 1H and 13C nuclear magnetic resonance.

D M LilleyB M Richards


Histone self-aggregation processes have been studied by 13C and 1H nuclear magnetic resonance (NMR) as a function of ionic strength and protein concentration. Thus has led to a model involving apolar aggregation between structured regions of these molecules. This analysis supports the validity of the acquistion of conformational data on histones by the simulation of 13C NMR spectra at high concentration. Solution conformations for histones F2B and F3 are presented.


Jun 1, 1977·Nucleic Acids Research·D M Lilley, K Tatchell
Jan 1, 1978·Nucleic Acids Research·W O WeischetH Klump
Oct 1, 1978·Nucleic Acids Research·D R BurtonI O Walker
Nov 15, 1976·European Journal of Biochemistry·T TancrediC Crane-Robinson
Jan 1, 1980·CRC Critical Reviews in Biochemistry·J E Coleman, J L Oakley
Dec 6, 1976·Biochemical and Biophysical Research Communications·B E Chapman, W J Moore
Dec 11, 1979·Biochemistry·S C ElginL E Hood
Jan 25, 1979·Biochimica Et Biophysica Acta·O W Howarth

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