An investigation of the effect of an essential oil mouthrinse on induced bacteraemia: a pilot study

Journal of Clinical Periodontology
Daniel H FineMarcelo W B Araujo

Abstract

This pilot study was designed to assess the effect of an essential oil antiseptic mouthrinse (EOM) in reducing bloodstream bacteria after chewing an apple. From a panel of 200, we screened 62 individuals with mild-to-moderate gingivitis. Twenty-two individuals who showed a bacteraemia after chewing an apple were enrolled. Subjects were recalled, instructed to chew an apple, had blood drawn (first baseline), and were randomly assigned EOM or a control (C) treatment for 2 weeks. Subjects were recalled, given an apple, and had blood taken for bacterial counts. Following a 1-week fluoride dentifrice wash-out, subjects were recalled, given the apple challenge, had blood drawn (second baseline), assigned the alternate treatment, and recalled for testing. Differences between baseline and 2-week post-treatment (EOM versus C) in blood-borne bacteria were assessed by analysis of covariance. Mean aerobic blood-borne bacteria decreased by 68.5% (17.7 viable counts from baseline; p<0.001), while anaerobic counts decreased by 70.7% (14.5 mean viable counts from baseline; p<0.001) for the EOM treatment. No reduction was seen for the C treatment. This double-blind, placebo-controlled, randomized, 2-week cross-over study showed that rinsing wit...Continue Reading

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Citations

May 30, 2014·PloS One·Anna Carolina Ratto Tempestini HorlianaGiuseppe Alexandre Romito
May 3, 2013·Journal of Periodontology·Leticia ReyesAnn Progulske-Fox
Nov 19, 2011·Journal of Clinical Periodontology·Inmaculada TomásNikolaos Donos
Nov 10, 2012·Journal of Clinical Periodontology·William ZhangBrad Curtis
May 3, 2013·Journal of Clinical Periodontology·Leticia ReyesAnn Progulske-Fox
Mar 15, 2011·Archives of Oral Biology·Sang-Eun MoonJeong-Dan Cha
Aug 30, 2012·Brazilian Oral Research·José Roberto CortelliMarcelo Werneck Barata de Araujo
Dec 7, 2017·Journal of Applied Oral Science : Revista FOB·Rodrigo Dalla Pria BalejoSheila Cavalca Cortelli
Nov 3, 2010·International Journal of Dental Hygiene·Maria Perno Goldie
Sep 14, 2016·Biomédica : revista del Instituto Nacional de Salud·Anna Carolina Ratto-TespestiniMagda Feres
Aug 15, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Julio CarrionChristopher W Cutler
Aug 12, 2017·Journal of Clinical Periodontology·Prem K SreenivasanDaniel H Fine

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