An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
J A L JenesonKlaas Nicolay

Abstract

An MR-compatible ergometer was developed for in-magnet whole-body human exercise testing. Designed on the basis of conventional mechanically braked bicycle ergometers and constructed from nonferrous materials, the ergometer was implemented on a 1.5-T whole-body MR scanner. A spectrometer interface was constructed using standard scanner hardware, complemented with custom-built parts and software to enable gated data acquisition during exercise. High-quality 31P NMR spectra were reproducibly obtained from the medial head of the quadriceps muscle of the right leg of eight healthy subjects during two-legged high-frequency pedaling (80 revolutions per minute) at three incremental workloads, including maximal. Muscle phosphocreatine content dropped 82%, from 32.2+/-1.0 mM at rest to 5.7+/-1.1 mM at maximal workload (mean+/-standard error; n=8), indicating that the majority of quadriceps motor units were recruited. The cardiovascular load of the exercise was likewise significant, as evidenced by heart rates of 150 (+/-10%) beats per minute, measured immediately afterward. As such, the newly developed MR bicycling exercise equipment offers a powerful new tool for clinical musculoskeletal and cardiovascular MR investigation. The basic d...Continue Reading

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Citations

Jan 29, 2011·Skeletal Radiology·Reza Hosseini GhomiMartin Torriani
Aug 24, 2011·European Journal of Applied Physiology·J P J SchmitzD F Stegeman
Dec 13, 2017·Frontiers in Physiology·Adrianus J BakermansJeroen A L Jeneson
Jun 9, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ying HaoJing Fang
Jan 26, 2013·Journal of Magnetic Resonance Imaging : JMRI·Florian von Knobelsdorff-BrenkenhoffJeanette Schulz-Menger
Jul 11, 2020·Current Opinion in Cardiology·Yin GeAndrew T Yan
Oct 15, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Tamer A BashaReza Nezafat
Apr 7, 2016·Interface Focus·Kalyan C VinnakotaJeroen A L Jeneson
Dec 29, 2015·Experimental Physiology·Maarten WerkmanErik Hulzebos
Sep 27, 2018·Sports Medicine·Carlo De InnocentiisSabina Gallina
Oct 6, 2009·Experimental Physiology·Joep P J SchmitzJeroen A L Jeneson
Dec 28, 2021·European Journal of Heart Failure·Kirsten T NijholtB Daan Westenbrink

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