Abstract
Herein, we use a combination of thermodynamic and spectroscopic measurements to investigate the interactions of Hofmeister anions with a thermoresponsive polymer, poly(N,N-diethylacrylamide) (PDEA). This amide-based polymer does not contain an NH moiety in its chemical structure and, thus, can serve as a model to test if anions bind to amides in the absence of an NH site. The lower critical solution temperature (LCST) of PDEA was measured as a function of the concentration for 11 sodium salts in aqueous solutions, and followed a direct Hofmeister series for the ability of anions to precipitate the polymer. More strongly hydrated anions (CO3(2-), SO4(2-), S2O3(2-), H2PO4(-), F(-), and Cl(-)) linearly decreased the LCST of the polymer with increasing the salt concentration. Weakly hydrated anions (SCN(-), ClO4(-), I(-), NO3(-), and Br(-)) increased the LCST at lower salt concentrations but salted the polymer out at higher salt concentrations. Proton nuclear magnetic resonance (NMR) was used to probe the mechanism of the salting-in effect and showed apparent binding between weakly hydrated anions (SCN(-) and I(-)) and the α protons of the polymer backbone. Additional experiments performed by attenuated total reflection Fourier tra...Continue Reading
References
Nov 1, 1985·Quarterly Reviews of Biophysics·K D Collins, M W Washabaugh
Feb 23, 1972·Journal of the American Chemical Society·P K Nandi, D R Robinson
Feb 23, 1972·Journal of the American Chemical Society·P K Nandi, D R Robinson
Mar 8, 2003·Quarterly Reviews of Biophysics·Andreas Barth, Christian Zscherp
Jun 5, 1965·Journal of the American Chemical Society·D R ROBINSON, W P JENCKS
Oct 13, 2005·Journal of the American Chemical Society·Yanjie ZhangPaul S Cremer
Jul 18, 2008·The Journal of Physical Chemistry. B·Laurel M Pegram, M Thomas Record
Oct 10, 2008·The Journal of Physical Chemistry. B·Younhee ChoPaul S Cremer
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Berk Hess, Nico F A van der Vegt
Aug 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Yanjie Zhang, Paul S Cremer
Jan 9, 2010·Annual Review of Physical Chemistry·Yanjie Zhang, Paul S Cremer
Apr 7, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Nadine SchwierzRoland R Netz
Jun 15, 2011·Physical Chemistry Chemical Physics : PCCP·Drew F ParsonsBarry W Ninham
Jun 22, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Branden A Deyerle, Yanjie Zhang
Oct 22, 2011·The Journal of Physical Chemistry. B·Elena A Algaer, Nico F A van der Vegt
Jan 19, 2012·Chemical Reviews·Pierandrea Lo Nostro, Barry W Ninham
Jun 13, 2012·Journal of the American Chemical Society·Kelvin B RembertPaul S Cremer
Jun 16, 2012·The Journal of Physical Chemistry. B·Jaibir KherbPaul S Cremer
Dec 22, 2012·Molecular Pharmaceutics·Jian Zhang-van EnkJifeng Zhang
Mar 23, 2013·Journal of the American Chemical Society·Halil I OkurPaul S Cremer
May 28, 2013·Biomacromolecules·Wafa HassounehAshutosh Chilkoti
Jun 6, 2013·Journal of the American Chemical Society·Blake M Rankin, Dor Ben-Amotz
Jun 19, 2013·The Journal of Physical Chemistry. B·Jana PaterováPavel Jungwirth
Jun 26, 2013·Faraday Discussions·Blake M RankinDor Ben-Amotz
Jun 26, 2013·Faraday Discussions·Anil Kurut, Mikael Lund
Jan 28, 2014·The Journal of Physical Chemistry Letters·Jana HladílkováPavel Jungwirth
Mar 22, 2014·Nature Chemistry·Pavel Jungwirth, Paul S Cremer
Aug 26, 2014·The Journal of Physical Chemistry. B·Jan Heyda, Joachim Dzubiella
Aug 19, 2015·The Journal of Physical Chemistry Letters·Eva PluhařováPavel Jungwirth
Dec 19, 2013·The Journal of Physical Chemistry Letters·Wen Jun Xie, Yi Qin Gao
Citations
Feb 18, 2016·Chemical Communications : Chem Comm·Yun XuGuangming Liu
Nov 28, 2015·Angewandte Chemie·Matthew J LangtonPaul D Beer
Dec 8, 2015·Journal of Colloid and Interface Science·Saeed Zajforoushan Moghaddam, Esben Thormann
May 31, 2016·Angewandte Chemie·Vasileios BalosJohannes Hunger
Jan 6, 2017·Journal of the American Chemical Society·Jan HeydaPaul S Cremer
Jan 18, 2017·The Journal of Physical Chemistry. B·Halil I OkurPavel Jungwirth
Jan 21, 2017·The Journal of Physical Chemistry. B·Nicolas O JohnsonYanjie Zhang
Apr 28, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Saeed Zajforoushan Moghaddam, Esben Thormann
Sep 27, 2018·Soft Matter·Leonor Pérez-FuentesCarlos Drummond
Nov 8, 2018·Angewandte Chemie·Vasileios BalosJohannes Hunger
Feb 13, 2019·Physical Chemistry Chemical Physics : PCCP·Edwin C JohnsonErica J Wanless
Jan 26, 2018·Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology·Shigeru Oshima
Apr 16, 2020·Soft Matter·Haiyang Yuan, Guangming Liu
May 28, 2020·Physical Chemistry Chemical Physics : PCCP·Xiaoshuang YanJiwen Feng
Jan 17, 2020·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Olga A FranciscoMazdak Khajehpour
Dec 3, 2016·Soft Matter·Lvdan LiuGuangming Liu
Oct 30, 2020·Polymers·Xue LiuWangqing Zhang
Oct 31, 2020·Journal of the American Chemical Society·Ellen E BrucePaul S Cremer
Dec 16, 2016·The Journal of Physical Chemistry. B·Bradley A RogersYanjie Zhang
Mar 20, 2019·The Journal of Physical Chemistry. B·Ki Chul Park, Takehiko Tsukahara
Mar 29, 2019·Journal of the American Chemical Society·Ellen E BruceNico F A van der Vegt
Oct 25, 2016·ACS Omega·Jordan W ByeMike P Williamson
Dec 28, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Ki Chul Park, Takehiko Tsukahara
Aug 4, 2018·The Journal of Physical Chemistry. B·Christopher S HaleVictor G J Rodgers
Oct 27, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Mitsuhiro MatsumotoYasuyuki Tsuboi
Jan 8, 2021·The Journal of Physical Chemistry. B·Ellen E BruceNico F A van der Vegt
Nov 3, 2021·Nature Chemistry·Bradley A RogersPaul S Cremer