An obscure cause of gastrointestinal bleeding: Renal cell carcinoma metastasis to the small bowel

International Journal of Surgery Case Reports
Robyn L GorskiAla' Abdel Jalil

Abstract

Renal cell carcinoma metastasis to the small intestine is a rare condition. It usually results in gastrointestinal bleeding and it could happen many years after the diagnosis with renal cell cancer. Treatment includes surgery as well as targeted agents such as tyrosine kinases. We report here the case of an 82-year-old man with a past medical history of high-grade renal cell carcinoma and right nephrectomy 6 years earlier, who presented with recurrent episodes of syncope and black stools. He underwent esophagogastroduodenoscopy (EGD) and colonoscopy without evident source of bleeding. Video capsule endoscopy (VCE) showed three bleeding lesions in the jejunum and ileum. Push enteroscopy revealed a proximal jejunum bleeding mass that was suspicious for malignancy. Histopathology demonstrated poorly differentiated carcinoma. Given the patient's history of high-grade renal cell carcinoma, and similarity of histologic changes to the old renal cell cancer specimen, metastatic renal cell carcinoma was felt to be the responsible etiology.

References

Jun 1, 2008·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Wan Kyu EoSung Il Choi
Nov 10, 2010·Case Reports in Gastroenterology·Viplove SenadhiRodrigo Erlich
Feb 1, 2011·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Tsutomu TakedaSumio Watanabe
May 18, 2011·Case Reports in Gastroenterology·Tarun RustagiMark Versland
Jul 7, 2011·World Journal of Gastrointestinal Oncology·Sujith V CherianStephen K Landas
Jan 6, 2012·Case Reports in Oncology·Luis CharaJavier Cassinello
Dec 1, 2012·Case Reports in Gastrointestinal Medicine·Muhammed Hameed ThoufeeqJason Jennings

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Citations

May 2, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Hyo Jung ParkHyun Kwon Ha
Jan 9, 2016·Asian Pacific Journal of Cancer Prevention : APJCP·Natthakan TangkittikasemVarayu Prachayakul
Jul 9, 2020·ACG Case Reports Journal·Brittany M MitchellAlberto Rubio-Tapia

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Methods Mentioned

BETA
surgical resection
biopsy

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