An observational 7-year study of continuous subcutaneous insulin infusion for the treatment of type 1 diabetes mellitus

Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición
Panagiota PapargyriJosé Manuel Miralles García

Abstract

This work reports the experience with use of continuous subcutaneous insulin infusion (CSII) in 112 type 1 diabetic patients followed up for 7 years and previously treated with multiple daily insulin injections (MDII). A retrospective, observational study in 112 patients with diabetes mellitus treated with CSII from 2005 to 2012, previously treated with MDII and receiving individualized diabetic education with a specific protocol. Variables analyzed included: prevalence of the different indications of pump treatment; mean annual HbA1c and fructosamine values before and after CSII treatment; and hypoglycemia frequency and symptoms. The most common reason for pump treatment was brittle diabetes (74.1%), followed by frequent or severe hypoglycemia or hypoglycemia unawareness (44.6%). Other indications were irregular food intake times for professional reasons (20.2%), dawn phenomenon (15.7%), pregnancy (12.3%), requirement of very low insulin doses (8.9%), and gestational diabetes (0.9%). HbA1c decreased by between 0.6% and 0.9%, and fructosamine by between 5.1% and 12.26%. Nine percent of patients experienced hypoglycemia weekly, 24% every two weeks, and 48% monthly. No hypoglycemia occurred in 19% of patients. Only 10% had neurog...Continue Reading

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Citations

Aug 8, 2014·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Matthew F BouchonvilleDavid S Schade
Apr 22, 2017·Diabetic Medicine : a Journal of the British Diabetic Association·U AnyanwaguE G Wilmot
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Feb 3, 2020·Endocrinología, Diabetes Y Nutrición·Jesus Moreno-FernandezFrancisco Javier Gómez-Romero

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