An observational and comparative study on intraductal papillary mucinous neoplasm of the biliary tract and the pancreas from a Chinese cohort

Clinics and Research in Hepatology and Gastroenterology
Ming WangNarasimha Murthy Trishul

Abstract

Intraductal papillary mucinous neoplasms of the biliary tract (BT-IPMNs) are unique but very rare biliary tumors. The relationship between BT-IPMNs and intraductal papillary mucinous neoplasm of the pancreas (P-IPMNs) was still unclear and controversial. We aimed to evaluate the clinical, radiological, histopathological, and prognostic characteristics of BT-IPMNs and P-IPMNs to achieve a better understanding of these two rare bilio-pancreatic diseases and their connections. Data of a total of 116 patients who were all surgically treated and histopathologically diagnosed as BT-IPMNs or P-IPMNs from January 2004 to December 2014 in our single institution was all retrospectively collected and analyzed. This study respectively enrolled 32 patients with BT-IPMNs and 84 ones with P-IPMNs. The differences between BT-IPMNs and P-IPMNs in age, sex ratios, clinical presentation, elevated tumor markers and proportion of malignancy were not statistically significant (P>0.05), while the tumor diameter of BT-IPMNs was notably smaller than P-IPMNs (1.72cm, 4.56cm, respectively; P=0.028). Patients with BT-IPMNs were more likely manifest the symptoms of cholangitis, compared to those with P-IPMNs who showed pancreatitis (75%, 30%, respectively;...Continue Reading

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Citations

May 15, 2016·Clinics and Research in Hepatology and Gastroenterology·Ana RuizCatherine Merzeau
Jan 23, 2017·Seminars in Diagnostic Pathology·Yasuni Nakanuma, Yoshiko Sudo
Aug 17, 2018·The Journal of International Medical Research·Xin WuYupei Zhao
Feb 2, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Argha ChatterjeeFrank H Miller

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