An observational study of cardiovascular characteristics of long-term end-stage renal disease survivors

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
W F OwenB M Brenner

Abstract

Long-term survival with end-stage renal disease (ESRD) on dialysis is uncommon, mainly because of the high mortality associated with cardiovascular disease. To define the clinical characteristics of long-term ESRD survivors, especially their cardiovascular risk profile, patients were identified with > or = 15 years of ESRD having at least 10 years on dialysis. Seventeen patients were identified with a duration of ESRD of 21.0 +/- 4.3 years (mean +/- SD). The age of the patients at the initiation of dialysis was 38.4 +/- 14.5 years. Eighty-eight percent of the survivors were white, and 12% were African-American. The primary causes of ESRD were glomerulonephritis, 65%; polycystic kidney disease, 18%; tubulointerstitial/obstructive disorders, 12%; and hypertension, 6%. At the initiation of dialysis, these long-term survivors presented with a low prevalence of cardiovascular risk factors (hypertension, 53%; diabetes mellitus, 0%; active smoking, 11.8%; family history, 25%) and cardiovascular disease (coronary heart disease, 5.9%; congestive heart failure, 5.9%; arrhythmias, 0%; peripheral vascular disease, 0%; and cerebrovascular disease, 5.9%). In addition, only 6.6% of the long-term ESRD survivors presented with systolic blood pr...Continue Reading

References

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Citations

Dec 20, 2005·Journal of Korean Medical Science·Chan-Duck KimYong-Lim Kim
Jul 27, 2012·Clinical Kidney Journal·James HeafHenrik Post Hansen
May 22, 2010·Renal Failure·Halil CiftciHalil Oncel
Nov 10, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·I B Salusky, W G Goodman
May 18, 2000·The New England Journal of Medicine·W G GoodmanI B Salusky
Jan 29, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Isidro B Salusky, William G Goodman
Mar 22, 2018·Journal of Breath Research·Santanu MandalManik Pradhan
Mar 28, 2007·Molecular and Cellular Biochemistry·Abdishakur M AbdulleJaipaul Singh
Sep 25, 2019·Journal of Clinical Medicine·Giulia SantagatiGiorgina Barbara Piccoli
Mar 1, 2013·Journal of Breath Research·Tina GoerlJochen K Schubert
Dec 5, 1998·Kidney International. Supplement·J M Lopez-GomezR Perez-Garcia
Mar 13, 2003·Kidney International·Stephan R Orth, Dominik E Uehlinger
Mar 6, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Chike Nathan OkechukwuFriedrich K Port
Dec 14, 1999·Kidney International·C O Stehman-BreenD Gipson
Mar 18, 2000·Kidney International·G M ChertowE G Lowrie

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