Abstract
Incidence of jaundice in pregnancy, including underlying chronic liver diseases, is 3-5%. However, the maternal mortality rate in some conditions can be as high as 18% in acute fatty liver of pregnancy and 22% in hepatitis E in pregnancy. This is an observational study of the demographics, obstetrical profile, aetiology, maternal morbidity, mortality and neonatal outcomes in pregnancies complicated with jaundice. This is an observational study conducted in Department of Obstetrics and Gynaecology of a tertiary care hospital, situated amidst the biggest urban slum in Mumbai spanning over 1 year from January 2016 to December 2016. All registered, unregistered and transferred patients with abnormal liver function tests excluding patients with chronic liver diseases were included in this study. Most of the cases of jaundice in pregnancy were seen in primigravida (51%) and age group of 20-30 years (58%). Fifty-three percentage of cases were referred or transferred from periphery hospitals. Hepatitis E was the most common cause (42%) of jaundice in pregnancy. Complications like disseminated intravenous coagulopathy, postpartum haemorrhage, hepatic encephalopathy and hepatoportal hypertension were seen in 65% of cases. Maternal mortal...Continue Reading
References
Feb 12, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J Eileen Hay
Oct 18, 2008·Journal of Hepatology·Harshad DevarbhaviLakshmi Padmanabhan
Mar 31, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Marc G GhanyUNKNOWN American Association for the Study of Liver Diseases
Jun 23, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Handan CelikErdal Malatyalýodlu
Apr 7, 2010·Molecular Genetics and Metabolism·Petra M EskelinTiina A Tyni
Aug 4, 2011·Clinics and Research in Hepatology and Gastroenterology·Andreas E KremerUlrich Beuers
Oct 30, 2013·Nutrition Reviews·Arun Jeyabalan
Mar 13, 2014·Journal of Medical Virology·Salam Gyaneshwori DeviShashi Sharma
Dec 3, 2014·American Journal of Obstetrics and Gynecology·Sascha R EllingtonAthena P Kourtis
Mar 15, 2015·Integrated Blood Pressure Control·Fred A EnglishFergus P McCarthy
Mar 27, 2015·Journal of Family Medicine and Primary Care·Auda Fares
Oct 11, 2015·American Journal of Obstetrics and Gynecology·Jodie Dionne-OdomNeil S Silverman
Dec 15, 2015·Journal of Hepatology·Rachel H WestbrookCatherine Williamson
May 14, 2016·Chinese Medical Journal·Yan-Ping ZhangRong Zhou
Jan 1, 2009·Medical Journal, Armed Forces India·B NandiR K Ganjoo
Citations
Dec 6, 2019·Journal of Family Medicine and Primary Care·Sohini DasRamya Iyadurai
Jul 30, 2020·BMC Pregnancy and Childbirth·Jean Joel BignaRichard Njouom
Nov 28, 2019·BMC Pregnancy and Childbirth·Derartu D TekelaGizeaddis L Simegn