An open label clinical trial to evaluate the utility of a hydrolysed fish and rice starch elimination diet for the diagnosis of adverse food reactions in dogs

Veterinary Dermatology
Irina Matricoti, Chiara Noli

Abstract

The diagnosis of adverse food reaction (AFR) is based on an eight week elimination diet (ED) and is confirmed by relapse upon re-challenge with the previously fed diet. Hydrolysed EDs are commonly used for this purpose. To evaluate a commercially available hydrolysed fish protein and rice starch ED for the diagnosis of AFR. Fifty nonseasonally pruritic dogs. Pruritus was assessed with a Visual Analog Scale, lesions with the Canine Atopic Dermatitis Lesions Index and quality of life with a validated questionnaire on days 0 and 56. Antimicrobial treatments were permitted during the first four weeks, and corticosteroids and oclacitinib during the first six weeks. Dogs showing at least 50% pruritus improvement were separately challenged with their prior diet, fish and rice. Thirty eight dogs completed the ED, four were dropped out due to worsening clinical signs, three to low palatability and five were lost to follow-up. In 24 dogs, pruritus improved by >50% and 22 underwent dietary challenges. Of these, 15 reacted to their prior diets and were diagnosed with AFR, whereas seven did not relapse (and a diagnosis of AFR was considered to be doubtful). Five dogs reacted to fish and four to rice. Of the 14 dogs in which pruritus did not...Continue Reading

References

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May 10, 2013·Journal of Animal Physiology and Animal Nutrition·R RicciF Mutinelli
Apr 18, 2015·Acta Veterinaria Scandinavica·Isabella R MaineKin-Chow Chang
Aug 19, 2015·Veterinary Dermatology·Chiara NoliUNKNOWN Skinalia Clinical Research Group
Mar 2, 2017·Veterinary Dermatology·Christa Horvath-UngerboeckStefanie Handl
Aug 5, 2017·Veterinary Dermatology·Olivier RoitelNicolas Couturier

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Citations

Jul 3, 2021·Animals : an Open Access Journal From MDPI·Blanka Premrov BajukBreda Jakovac Strajn

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Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.