An open-label study of escitalopram in body dysmorphic disorder

International Clinical Psychopharmacology
Katharine A Phillips

Abstract

Body dysmorphic disorder (BDD) is a relatively common and impairing disorder. Selective serotonin reuptake inhibitors (SRIs) appear selectively efficacious for BDD, but pharmacotherapy research is limited, and escitalopram has not been studied. Fifteen subjects with BDD were treated with escitalopram and assessed with reliable and valid measures. BDD symptoms significantly improved (P<0.001), and 73.3% (n=11) of subjects were responders. Of the subjects, 46.7% were very much improved, and 33.3% were much improved. Depressive symptoms, delusionality, functioning and quality of life also significantly improved. Escitalopram was well tolerated. These preliminary data suggest that escitalopram is safe and efficacious for BDD.

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Citations

Mar 12, 2008·Wiener medizinische Wochenschrift·Wolfgang HarthUwe Gieler
May 4, 2011·Current Psychiatry Reports·Ulrike Buhlmann, Anna Winter
Dec 9, 2008·International Clinical Psychopharmacology·Katharine A Phillips, Megan M Kelly
May 11, 2013·CNS Spectrums·Katharine A PhillipsDan J Stein
May 21, 2013·Clinical Psychology Review·Andrea S HartmannSabine Wilhelm
Aug 26, 2014·The Psychiatric Clinics of North America·Angela FangSabine Wilhelm
Jul 3, 2013·The Journal of Nervous and Mental Disease·Katharine A PhillipsJane L Eisen
Aug 13, 2011·La Presse médicale·Jean TignolBruno Aouizerzate
Mar 29, 2011·Child and Adolescent Psychiatric Clinics of North America·Katharine A Phillips, Jamison Rogers
May 7, 2013·Comprehensive Psychiatry·Andri S BjornssonKatharine A Phillips
Feb 16, 2010·Comprehensive Psychiatry·Serafino G MancusoDavid J Castle
Jul 1, 2010·Psychiatric Annals·Katharine A Phillips
Oct 31, 2008·Comprehensive Psychiatry·Elizabeth R DidieKatharine A Phillips
Sep 20, 2007·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Wolfgang HarthAndreas Hillert
Sep 1, 2007·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Wolfgang Harth, Barbara Hermes
Dec 18, 2007·Journal of the European Academy of Dermatology and Venereology : JEADV·W HarthU Gieler
Dec 30, 2014·Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie·Katharina GrauMarc Allroggen
Jul 24, 2012·Journal of Psychiatric Research·Katharine A PhillipsSteven A Rasmussen
Jan 13, 2015·Annual Review of Clinical Psychology·Angela Fang, Sabine Wilhelm
Apr 2, 2008·Journal of Psychiatric Research·Katharine A PhillipsRobert L Stout
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May 2, 2009·CNS Spectrums·Katharine A Phillips, William Menard
May 1, 2019·Expert Opinion on Pharmacotherapy·Nancy DongEric Hollander

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