PMID: 11898336Mar 20, 2002Paper

An origin of DNA replication from streptomycete phage phi U1

Folia Microbiologica
J FarkasovskáJ Timko

Abstract

A DNA fragment from phage phi U1 containing an origin of DNA replication was identified. This fragment, designated ori, was able to support the maintenance in Streptomyces lividans of a plasmid lacking a functional Gram-positive ori. The sequence of the minimal ori fragment was determined and analyzed. The minimal fragment conferring replication origin function contained a number of direct and inverted repeats. The absence of an open reading frame in this ori fragment indicates that host factors alone were sufficient to initiate replication at ori.

References

Nov 24, 1979·Nucleic Acids Research·H C Birnboim, J Doly
Jan 1, 1985·Molecular & General Genetics : MGG·T MorinoH Saito
Apr 1, 1996·Journal of Bacteriology·C W Howe, M C Smith
Jun 1, 1996·Microbiology·Christine W Howet, Margaret C M Smith
Mar 1, 1997·Letters in Applied Microbiology·C R Myers, J M Myers
Jun 5, 1998·Microbiology·Dagmara JakimowiczJolanta Zakrzewska-Czerwinńska
Sep 13, 2000·Folia Microbiologica·E PilipcinecI Mikula

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Citations

Nov 4, 2008·The Journal of Hand Surgery, European Volume·S Goldsmith, S S Yang
May 15, 2004·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·L Adolfsson, B Povlsen

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