Abstract
In a group of 22 healthy pigs aged between 4 and 6 months, 2 pigs became ill with high fever, complete anorexia, cough and abnormal swaying movements on 22 June 2015. One of them died on June 24 and the second died on July 3. Shortly after, the remaining pigs also fell ill and died from the same illness by 10 August 2015. We investigated the aetiology, epidemiological and clinical features of the outbreak. We recorded the clinical signs and symptoms for each pig with the date of onset of illness. Veterinarians conductedpost-mortemexaminations on the 12 dead pigs, they collected tissue samples from the dead pigs and placed them in a tube containing 1 mL of nucleic acid extraction buffer (lysis buffer). We tested all the tissue samples by real-time reverse transcription polymerase chain reaction (rRT-PCR) to detect classical swine fever virus (CSFV) because the animals' symptoms matched those of this disease. We also conducted a phylogentic analysis of the nucleotide sequence of the E2 gene segment of CSFV detected in a lung tissue sample. The attack rate (22/22) and the case fatality were 100%. The predominant symptoms of the disease included high fever, cough, diarrhoea and swaying movements of the hind legs prior to death. Of ...Continue Reading
References
Aug 1, 1992·Tropical Animal Health and Production·R M Gatenby, P B Chemjong
Aug 1, 1989·Virology·G MeyersH J Thiel
Sep 30, 1999·The Veterinary Record·H LaevensA de Kruif
Apr 28, 2000·Veterinary Microbiology·S EdwardsJ Westergaard
Apr 28, 2000·Veterinary Microbiology·D J PatonS Belák
Apr 28, 2000·Veterinary Microbiology·V KadenG Strebelow
Oct 12, 2000·Vaccine·J DewulfA de Kruif
Mar 6, 2003·The Veterinary Journal·V MoennigI Greiser-Wilke
Nov 6, 2003·Veterinary Microbiology·J T van Oirschot
Jun 30, 2005·Animal Health Research Reviews·Irene Greiser-Wilke, Volker Moennig
Feb 27, 2008·BMC Veterinary Research·Gert Jan BoenderMart C M de Jong
Oct 20, 2009·Veterinary Microbiology·S S PatilK Prabhudas
Nov 10, 2009·Comparative Immunology, Microbiology and Infectious Diseases·Dilip Kumar SarmaShiv Chandra Dubey
Mar 6, 2010·Acta Virologica·G S DesaiA K Tiwari
May 17, 2011·Preventive Veterinary Medicine·Kinzang DukpaTrevor M Ellis
Jul 19, 2011·Transactions of the Royal Society of Tropical Medicine and Hygiene·Kashi N PrasadVimal K Paliwal
Jul 10, 2012·The Veterinary Record·Vijay Chandra JhaDinesh Kumar Singh
Aug 29, 2012·Transboundary and Emerging Diseases·J-Y SongD J An
Apr 24, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Da-Liang JiangChangchun Tu
May 6, 2014·Veterinary Microbiology·Yuzi LuoHua-Ji Qiu
Sep 26, 2014·PLoS Neglected Tropical Diseases·Salah Uddin KhanEmily S Gurley
Jul 1, 2015·EcoHealth·Nazmun NaharStephen P Luby
Mar 11, 2017·Acta Tropica·Elina KhatoonSachin Kumar
Apr 22, 2017·Viruses·Sandra BlomeMartin Beer
Citations
May 5, 2018·Tropical Animal Health and Production·Vinod Kumar SinghSharad Kumar Yadav
Oct 6, 2019·Veterinary Microbiology·Wenjie GongChangchun Tu
Aug 12, 2021·Veterinary Medicine and Science·Xiaoru XieJun Justin Li