An outbreak of Kingella kingae infections associated with hand, foot and mouth disease/herpangina virus outbreak in Marseille, France, 2013

The Pediatric Infectious Disease Journal
Nawal El HoumamiPierre-Edouard Fournier

Abstract

Outbreaks of invasive Kingella kingae infections recently emerged as a new public health concern in daycare centers in Europe, USA and Israel. Despite this, no trigger factor has been yet identified, preventing the setting up of rational measures of control and prevention. We report an outbreak of K. kingae infections associated with hand, foot and mouth disease/herpangina outbreak, and we define the research and policy priorities. From April 22 to May 07, 2013, 5 toddlers presented successive osteo-articular infections in a daycare center in Marseille, France. Real-time polymerase chain reaction targeting the cpn60 gene of K. kingae was used to investigate suspected cases and the prevalence of oropharyngeal K. kingae carriage of their close contacts. The attack rate of the K. kingae infections outbreak was 23.7% (5/21) with no fatality. Positive real-time polymerase chain reaction targeting the cpn60 gene of K. kingae confirmed the diagnosis in 3 cases and revealed a rate of K. kingae oropharynx carriage in the index classroom of 94.4% (17/18) among daycare attendees not given antibiotic during the previous month, and of 76.9% (10/13) among staff in close contact. The eradication rate of K. kingae was 21.4% (3/14) among classm...Continue Reading

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Citations

Jan 7, 2016·Expert Review of Vaccines·Qun-ying MaoZhenglun Liang
Nov 28, 2015·Primary Care·Priya RamdassHarold F Farber
Dec 13, 2016·The Journal of Pediatrics·Pablo YagupskyPierre-Edouard Fournier
Dec 22, 2016·The Pediatric Infectious Disease Journal·Nawal El HoumamiPierre-Edouard Fournier
Oct 8, 2016·Molecular Oral Microbiology·J B KaplanN V Balashova
Mar 29, 2018·The Journal of Hand Surgery, European Volume·Nawal El HoumamiDimitri Ceroni
Jul 18, 2015·Pediatric Research·Rebecca Anderson de la LlanaDimitri Ceroni
Apr 6, 2018·The Pediatric Infectious Disease Journal·María Belén Hernández-RupérezJesús Saavedra-Lozano
Jun 25, 2019·The Pediatric Infectious Disease Journal·Anais ChosidowMathie Lorrot
Dec 15, 2015·The Pediatric Infectious Disease Journal·Nawal El HoumamiPierre-Edouard Fournier
Jan 12, 2020·Journal of the Pediatric Infectious Diseases Society·Pablo YagupskyRonen Fluss
Sep 19, 2017·Expert Review of Anti-infective Therapy·Pablo Yagupsky
Dec 15, 2020·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C KleinC Joseph

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