An outbreak of multidrug-resistant Pseudomonas aeruginosa in a burns service in the North of England: challenges of infection prevention and control in a complex setting

The Journal of Hospital Infection
V DecraeneR Puleston

Abstract

Burns patients are at high risk of nosocomial infection, and Pseudomonas aeruginosa is one of the most common causes of wound and systemic infections resulting in significant morbidity and mortality in burns patients. To describe an outbreak of multidrug-resistant P. aeruginosa (MDR-Pa) at a specialist burns service and highlight the challenges in identifying the reservoir of infection despite extensive epidemiological, microbiological, and environmental investigations. Multi-disciplinary outbreak control investigation. Following an inter-hospital transfer of a burns patient from another country, an admission screen revealed that the patient was colonized with MDR-Pa. Subsequently nine more patients contracted MDR-Pa in the period from November 2015 to September 2017. Given the relatively long gap between confirmation of the index and subsequent cases, it was not possible to identify with certainty the reservoirs and mechanisms of spread of infection, although contamination of the burns service environment and equipment are likely to be contributory factors. Preventing infection transmission in specialist burns services is highly challenging, and it may not always be possible to identify and eradicate the reservoirs of infectio...Continue Reading

Citations

Aug 2, 2019·Human Vaccines & Immunotherapeutics·Sarah M BakerLisa A Morici
May 7, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Felipe Fernández-CuencaÁlvaro Pascual
Aug 28, 2019·Antibiotics·Majdi N Al-HasanJulie Ann Justo
Apr 10, 2021·Annals of Plastic Surgery·Chunyang WangWilliam C Lineaweaver
Dec 1, 2020·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Steven L TaylorGeraint B Rogers
Sep 11, 2021·NPJ Biofilms and Microbiomes·Evgenia MaslovaRonan R McCarthy
Dec 25, 2019·The Journal of Hospital Infection·B PilmisJ-R Zahar

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