PMID: 3752095Jan 1, 1986Paper

An outbreak of N-hexane induced polyneuropathy among press proofing workers in Taipei

American Journal of Industrial Medicine
J D WangW Y Yeh

Abstract

The objective of this study was to determine the prevalence and the etiology of polyneuropathy observed among press proofing workers in Taipei. Neurological examinations of 59 workers, from 16 press proofing factories, were conducted. Fifty-four of those workers subsequently underwent studies of nerve conduction velocities. Samples of bulk solvent from the involved factories were analyzed for their contents using gas chromatography. Fifteen (25%) of the study group were found to have polyneuropathy. All 15 patients with polyneuropathy were from factories in which solvents containing n-hexane were regularly used, and there was a significant association between n-hexane concentration in the bulk samples and prevalence of polyneuropathy. The air concentration of n-hexane in one factory in which all six employees developed polyneuropathy was 190 ppm. Workers who were exposed to n-hexane at air levels of less than 100 ppm but who frequently worked overtime showed a significant slowing of motor nerve conduction velocities on median, ulnar, and peroneal nerves. Of 13 workers who regularly slept in the factory, 12 (92%) had polyneuropathy compared to three (7%) of 46 workers who did not sleep in the factory. The outbreak of polyneuropa...Continue Reading

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Citations

Jan 1, 1991·American Journal of Industrial Medicine·J D Wang
Jan 1, 1990·International Archives of Occupational and Environmental Health·T KawaiM Ikeda
Jan 1, 1991·International Archives of Occupational and Environmental Health·K MurataK Maeda
Jan 1, 1993·International Archives of Occupational and Environmental Health·A CardonaL Perbellini
Jan 1, 1995·Annals of Epidemiology·A M Sass-KortsakJ M Robertson
Jun 9, 2005·Reproductive Toxicology·Paul E KihaileJunichi Misumi
May 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·C M ChangS Y Chan
Jul 1, 1990·British Journal of Industrial Medicine·Y C Chang
Jan 1, 1991·British Journal of Industrial Medicine·Y C Chang
Feb 18, 2006·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Y ZhangY Zheng
Aug 7, 2012·Journal of Occupational Health·Masoud NeghabKambiz Khamoushian
Dec 20, 2012·Safety and Health at Work·Chi-Hung LiuChin-Chang Huang
Jul 1, 1989·Clinical EEG (electroencephalography)·C C Huang, N S Chu
Jan 1, 1988·Critical Reviews in Toxicology·A M Seppäläinen
Mar 1, 1996·Occupational and Environmental Medicine·J YuasaH Miyake
May 1, 1995·Toxicology and Industrial Health·G L Gist, J R Burg
Apr 25, 2007·Journal of Occupational and Environmental Hygiene·Michael P WilsonAlan E Hubbard
Apr 30, 2017·Journal of Medical Case Reports·Jo-Hui PanHung-Yi Chuang

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