An outbreak of Serratia marcescens septicaemia in neonatal intensive care unit in Gaza City, Palestine

The Journal of Hospital Infection
A M Kh Al JaroushaA S Al Afifi

Abstract

We performed a case-control study of Serratia marcescens incidence in the neonatal intensive care unit of a governmental Gaza Strip hospital from January to December 2005. S. marcescens was detected in the blood of 159 confirmed nosocomial cases of septicaemia, 70 (44%) neonates died due to S. marcescens infection and 89 recovered. The main clinical symptoms were hypothermia 38%; jaundice 42%; Apgar score 4 at 1 min in 29% of neonates; and Apgar score 5 at 5 min in 5%. Risk factors significantly associated with S. marcescens infection were birthweight <1,500 g (OR: 1.7; P=0.026); <37 weeks gestational age (OR: 2.0; P=0.002); and use of mechanical ventilation (OR: 2.3; P=0.001). Agar diffusion susceptibility testing indicated that S. marcescens was generally susceptible to imipenem, followed by ciprofloxacin and ofloxacin. We identified potential risk factors associated with development of neonatal sepsis and highlight the importance of appropriate infection control measures to prevent serious infection.

References

Jan 1, 1989·Scandinavian Journal of Infectious Diseases·C Watanakunakorn
May 1, 1988·The Journal of Pediatrics·R L RodwellD I Tudehope
Nov 1, 1986·Australian Paediatric Journal·C WakeA B Cull
Aug 1, 1987·Diagnostic Microbiology and Infectious Disease·E BouzaM Rodríguez-Créixems
Feb 1, 1993·American Journal of Infection Control·S OieA Koshiro
Jul 1, 1996·The Journal of Hospital Infection·C BosiC Bollet
Jun 1, 1997·The Journal of Hospital Infection·M L van OgtropC P van Boven
Nov 22, 1997·Journal of Medical Microbiology·A Hejazi, F R Falkiner
Apr 29, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·P BerthelotP Fargier
Feb 15, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M A AlmuneefL M Dembry
Oct 16, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Emmi SarvikiviHarri Saxén
Mar 7, 2006·The Journal of Hospital Infection·M D DavidA P Fraise

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Citations

Oct 7, 2011·Clinical Microbiology Reviews·Steven D Mahlen
Jan 24, 2012·American Journal of Infection Control·Helena C MaltezouAlkiviadis Vatopoulos
Sep 29, 2009·International Journal of Hygiene and Environmental Health·Alexander VoelzArne Simon
Nov 26, 2009·Journal of Chemotherapy·A DessìV Fanos
Dec 6, 2018·Advances in Medicine·Abdellatif DaoudiFadl Mrabih Rabou Maoulainine
Feb 23, 2019·International Journal of Environmental Research and Public Health·Maria Luisa CristinaAnna Maria Spagnolo
Oct 24, 2020·The Pediatric Infectious Disease Journal·Katherine M OttoliniElizabeth V Schulz

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