An overview of obesity in children with psychiatric disorders taking atypical antipsychotics.

Harvard Review of Psychiatry
Lauren ShinNancy Noyes

Abstract

Children with psychiatric illness are at greater risk for obesity than those in the general population. In part, this greater risk is due to the escalating use of psychotropic medications. Second-generation antipsychotics effectively treat mental illness but are associated with weight gain. Data for management of obesity in this population is lacking. Articles on obesity, mental illness, and obesity management were reviewed. Keywords included children, adolescents, obesity, weight gain, psychiatric illness, therapy, treatment, and antipsychotic. For pediatric obesity, educational, nutritional, behavioral, and family-based interventions were identified as nonpharmacological interventions. All nonpharmacological modalities indicate modest to moderate success in weight control or loss. Pharmacological agents, alone or with diet and exercise, appear promising in obesity management. Since there are limited intervention studies available for obese children with psychiatric illness, general childhood obesity studies may be referenced for trials in this population. Long-term efficacy and safety of these interventions are not yet available. Methodological constraints of prior studies include small sample sizes and the absence of randomi...Continue Reading

References

Aug 7, 1998·European Journal of Clinical Investigation·G PaolissoF D'Onofrio
Nov 10, 1998·Biological Psychiatry·S F Leibowitz, J T Alexander
Apr 30, 1999·The Journal of Clinical Psychiatry·D B AllisonL J Cheskin
Apr 6, 2001·Diabetes Care·S T Azar, M S Zantout
May 22, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·G FanghänelA Berber
Jul 5, 2001·Paediatric Drugs·S Daniels
Aug 10, 2001·Pediatric Clinics of North America·J A Yanovski
Oct 20, 2001·Journal of Child and Adolescent Psychopharmacology·J A FrazierZ M Nowlin
Nov 15, 2001·Obesity Research·W H Saris
Dec 6, 2001·Metabolism: Clinical and Experimental·J P KayS Holshouser
Dec 26, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·E MulsUNKNOWN ObelHyx Study Group
Apr 2, 2002·The American Journal of Psychiatry·John A MorrisonBruce A Barton
Jul 10, 2002·Obesity Research·Jennifer R McDuffieJack A Yanovski
Aug 22, 2002·Journal of Child and Adolescent Psychopharmacology·Gabriele MasiStefania Millepiedi
Nov 13, 2002·Journal of Child and Adolescent Psychopharmacology·Barbara L GraciousEric A Youngstrom
Dec 31, 2002·Psychoneuroendocrinology·R Tandon, M D Jibson
Apr 10, 2003·JAMA : the Journal of the American Medical Association·Brian Vastag
Apr 10, 2003·JAMA : the Journal of the American Medical Association·Robert I BerkowitzJoanna L Cronquist
Apr 10, 2003·JAMA : the Journal of the American Medical Association·Mark P EttingerHans-Peter Guler
Apr 22, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M KrempfJ-R Attali
Jul 29, 2003·Psychiatric Services : a Journal of the American Psychiatric Association·Betty VreelandRobert Stern
Aug 21, 2003·The Journal of Clinical Psychiatry·Christopher D O'KeefeHoney Weiss
Sep 6, 2003·Acta Psychiatrica Scandinavica·U WernekeS Wessely
Oct 9, 2003·Acta Psychiatrica Scandinavica·G FaulknerK Lloyd
Oct 18, 2003·Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing·Kimberly H LittrellCraig G Johnson
Oct 30, 2003·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Linmarie SikichJeffrey A Lieberman
Dec 25, 2003·Schizophrenia Research·Peter J WeidenDiana D McDonnell
Jan 30, 2004·Diabetes Care·UNKNOWN American Diabetes AssociationUNKNOWN North American Association for the Study of Obesity
Mar 11, 2004·Psychiatry and Clinical Neurosciences·Won-Myong BahkKwang-Soo Kim
Mar 12, 2004·Expert Opinion on Pharmacotherapy·Walker S Carlos Poston, John P Foreyt
May 22, 2004·Alimentary Pharmacology & Therapeutics·J ErdmannV Schusdziarra
Jun 9, 2004·Psychosomatic Medicine·Gilbert VilaMarie Christine Mouren-Siméoni
Jul 3, 2004·Journal of Clinical Psychopharmacology·Eduard VietaEsteve Brugue
Jul 13, 2004·Schizophrenia Research·Sanjay GuptaKari Lockwood
Aug 3, 2004·Pediatrics·Sarah Harvey O'BrienEvelyn Cohen Reis
Sep 7, 2004·Journal of Pediatric Psychology·Caroline BraetYves Rosseel
Dec 2, 2004·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Walter DeberdtAlan Breier
Dec 2, 2004·JAMA : the Journal of the American Medical Association·Brian L Strom

❮ Previous
Next ❯

Citations

Nov 3, 2009·Journal of Child and Adolescent Psychopharmacology·Antonella Gagliano, Gabriele Masi
Aug 26, 2009·Journal of Child and Adolescent Psychopharmacology·Gholson J Lyon, Barbara J Coffey
Jan 18, 2013·PloS One·L Oriana LinaresF Xavier Castellanos
Apr 7, 2011·Enfermedades infecciosas y microbiología clínica·César García-Rey
Aug 23, 2011·Pediatric Clinics of North America·Ann E Maloney
May 19, 2010·Child and Adolescent Psychiatric Clinics of North America·Ann E Maloney
Apr 16, 2011·International Journal of Mental Health Nursing·Andrea McCloughen, Kim Foster

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Antipsychotic-Induced Weight Gain

Antipsychotic-induced weight gain (aiwg) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. Here are the latest discoveries pertaining to AIWG.

Related Papers

Journal of the American Academy of Child and Adolescent Psychiatry
Christoph U Correll, Harold E Carlson
Journal of the American Academy of Child and Adolescent Psychiatry
Christoph U Correll
© 2022 Meta ULC. All rights reserved