PMID: 8945664Dec 1, 1996Paper

An ultrasonic technique for the measurement of the elastic moduli of human cornea

Journal of Biomechanics
H WangW V Chang

Abstract

In the hopes of reducing the unpredictability associated with refractive surgical procedures and ultimately improving surgical techniques, many investigators have attempted to determine the elastic moduli of the cornea. Techniques such as stress-strain tests of corneal strips and the measurement of mercury drop displacement in a whole eye under increasing pressure have resulted in a range of values for Young's modulus from 10(5) to 10(7) Nm-2. Both of these methods are limited because these mechanical tests cannot be performed in the physiological state and because of the large amount of force applied during testing. We used an ultrasonic technique to determine the elastic moduli of the human cornea. Two groups of six corneas prepared under different conditions (in saline and in dextran) were examined separately and the shear waves were generated and detected in these 12 human eye bank eyes. All the waveforms were digitized and saved in files of binary format. Fast Fourier transformation (FFT) was applied to calculate the speed and attenuation of the shear wave. Using the resulting wave speeds and attenuation coefficients, the Young's moduli of the corneal samples were calculated as (5.3 +/- 1.1) x 10(6) Nm-2 and (2.0 +/- 1.0) ...Continue Reading

Citations

Jun 1, 2000·Cornea·J KampmeierR Brinkmann
Jul 3, 2010·Journal of Biomaterials Science. Polymer Edition·Yuji TanakaKohji Nishida
Feb 22, 2005·Journal of Cataract and Refractive Surgery·Jun Liu, Cynthia J Roberts
Feb 22, 2005·Journal of Cataract and Refractive Surgery·Günther GrabnerWolfgang Husinsky
Sep 12, 2015·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Po-Jen ShihJia-Yush Yen
Jun 26, 2010·Journal of Magnetic Resonance Imaging : JMRI·Daniel V LitwillerRichard L Ehman
Apr 15, 2014·ISRN Ophthalmology·Nery Garcia-PortaJose Manuel González-Méijome
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Ana-Maria IonescuMaría del Mar Pérez
Jun 6, 2016·Ultrasonics·Li-Ke WangYong-Ping Zheng
Jul 31, 2007·Journal of Cataract and Refractive Surgery·Dolores OrtizJorge L Alió
Jun 20, 2002·Archives of Environmental Health·Yaw-Huei HwangChi-Ting Tseng
Jan 20, 2012·Annals of Biomedical Engineering·Hong Nam KimKahp-Yang Suh
Apr 20, 2004·Journal of Cataract and Refractive Surgery·Michael MrochenJoachim Löffler

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