PMID: 924089Jan 1, 1977Paper

An ultrastructural study of the Brunner's cyst

Gastroenterologia Japonica
M TauraS Iwanaga


A Brunner's cyst, removed from a 54-year-old woman, was studied by light and electron microscopy. The cyst was spherical, measured 1.5 cm in diameter and was located in the duodenal bulb. Histologically, the cyst, confined in the submucosa, consisted of a single layer of epithelial cells and connective tissue. The epithelial cells were composed of an orderly array of tall columnar cells containing basal round nuclei and fine granular cytoplasm. Ultrastructurally, the epithelial cells contained many secretory granules in the cytoplasm. Each secretory granule was membrane-bound and appeared electron-lucid with a dense core. They were small and sparse around the Golgi apparatus but large and numerous in the apical region. Multinucleated cells were intermingled with cells of the epithelial lining.


Aug 1, 1973·The American Journal of Digestive Diseases·R OsborneR M Lowman
Oct 1, 1960·Journal of Ultrastructure Research·H MOE


Jul 28, 2012·Digestive Diseases and Sciences·Kyungeun KimEunsil Yu
Dec 19, 2006·International Journal of Surgical Pathology·Heike VarnholtLiron Pantanowitz

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