An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis

doi:10.1101/001701

An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis

bioRxiv

Jan 9, 2014

Satdip KaurStephen J Royle

PMID: 990001701

DOI: 10.1101/001701

Abstract

Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear. Here we show that the mitotic shutdown is due to an unmet requirement for ...read more

Mentioned in this Paper

Metabolic Inhibition

Absent Renal Function

Tension

Microfilaments

Mitosis

Muscle Rigidity

Phosphorylation

Bark - plant part

Endocytosis Pathway

Clathrin-mediated Endocytosis

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