An unnatural PIP simulates growth factor signaling

Chemistry & Biology
Laura Swan

Abstract

In this issue of Chemistry & Biology, Laketa et al. describe the synthesis of a membrane permeant phosphoinositide lipid that acts to stimulate PI(3,4,5)P(3)-dependent signaling without the need of growth factor stimulation.

Related Concepts

Related Feeds

AKT Pathway

This feed focuses on the AKT serine/threonine kinase, which is an important signaling pathway involved in processes such as glucose metabolism and cell survival.

Related Papers

Progress in Biophysics and Molecular Biology
Jean-Marc DuboisBéatrice Rouzaire-Dubois
Biochemical and Biophysical Research Communications
E B McGowanT C Detwiler
© 2022 Meta ULC. All rights reserved