PMID: 8985643Jan 1, 1997Paper

An unusual case of elastofibroma oculi

Cornea
J K HsuW R Green

Abstract

A 22-year-old female college student from the southwestern United States was first seen with progressive fluffy white growths over both corneas nasally and a history of chronic allergies and extensive sun, wind, and chlorine exposure as a competitive swimmer. The lesions were superficial, elevated, crescent-shaped, vascularized, and extended from the limbal conjunctiva onto the peripheral cornea nasally. The lesions were composed of an unencapsulated thick fibrovascular pannus with numerous fibrocytes, chronic inflammatory cells and mast cells, and abundant linear and wavy elastinophilic profiles, but no adipose tissue. Ultrastructurally, the elastinophilic structures were immature elastic fibers arranged in globules and bundles within a thick collagenous matrix. No mature elastic fibers were found. A few areas of elastotic degeneration were also found. This lesion resembled elastofibromas that have been reported more commonly in the subcapsular region and only once in the ocular region. Previous reports debated whether the elastic material in elastofibromas is derived from excessive production of elastic fibers by activated fibrocytes or from elastotic degeneration of collagen. In our case, both processes occur and are presume...Continue Reading

Citations

Mar 20, 2010·Head and Neck Pathology·Konstantinos I TosiosIoannis G Koutlas
Jun 18, 2011·Head and Neck Pathology·Mark R DarlingGeorge P Wysocki
Oct 18, 2006·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Josefina MarcosEduardo L Rodríguez
Jun 29, 2010·Journal of Cutaneous Pathology·Cassiano Francisco Weege NonakaLeão Pereira Pinto
Apr 12, 2007·Diagnostic Cytopathology·Jan Janzen
Feb 5, 2010·The Journal of Bone and Joint Surgery. British Volume·M T R ParrattT W R Briggs

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