An unusual case of oral hirsutism in a patient with polycystic ovarian syndrome

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Felice FemianoGregorio Laino

Abstract

Hirsutism is the presence of terminal hair in women in a male-like pattern, which represents the clinical expression of an underlying excess of androgen (hyperandrogenism). Numerous conditions and serious diseases can result in high levels of circulating androgens, although the most common cause of hirsutism is polycystic ovary syndrome (PCOS). The following classic clinical features characterize PCOS: irregular menstrual periods, infertility, excess hair growth, and obesity. The diagnosis of this disease is related to the discovery of clinical signs that are confirmed by hematochemical examinations. We present a clinical case that is relatively unusual owing to the appearance of black hairs that are similar to nasal hair in the oral mucosa, which is an atypical location. This unusual case was considered to be oral hirsutism, and its presence constituted the essential element in the diagnosis of PCOS. The hypothesis proposed for this unusual condition could be correlated to the high rate of circulating testosterone that may have influenced and led to the development and appearance of the hair follicles in the oral mucosa.

References

Jun 1, 1980·Oral Surgery, Oral Medicine, and Oral Pathology·R A Baughman, P D Heidrich
Mar 1, 1997·Lancet·G Phillipov
May 1, 1997·Seminars in Reproductive Endocrinology·N A Cataldo
Jun 1, 1997·Baillière's Clinical Obstetrics and Gynaecology·T KealeyR Guy
Feb 7, 2004·The Journal of Clinical Endocrinology and Metabolism·R AzzizL R Boots
Jul 16, 2004·Postgraduate Medical Journal·P MaheuxR Matte
Aug 9, 2005·Current Medical Research and Opinion·Rodney P R Dawber
Dec 31, 2005·The Journal of Investigative Dermatology. Symposium Proceedings·Robert L Rosenfield
Jun 3, 2006·Drugs·Marcin Stankiewicz, Robert Norman
Jun 15, 2006·Best Practice & Research. Clinical Endocrinology & Metabolism·Bulent O Yildiz
Jun 15, 2006·Best Practice & Research. Clinical Endocrinology & Metabolism·Frank Z Stanczyk

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