An unusual case of tumor-to-cavernoma metastasis. A case report and literature review

Surgical Neurology
Chow H Patrick ChanRenate M Kalnins

Abstract

Metastases of systemic neoplasia to preexisting intracranial mass lesions are uncommon phenomena. Tumor-to-intracranial cavernoma metastases are even more unusual and rarely reported. We describe here a case of melanoma to intracranial cavernoma metastasis. A 39-year-old woman presented after an episode of generalized tonic-clonic seizure on a background of infrequent epilepsy. She was found to have a left parieto-occipital hemorrhagic lesion on imaging studies. The lesion was surgically removed and histopathology showed a metastatic melanoma within a cavernoma. This case report represents the third recorded case of tumor-to-intracranial cavernoma metastasis and the first melanoma to intracranial cavernoma metastasis. An extensive literature review of tumor-to-intracranial tumor metastases was conducted and disclosed an increase in reporting of the uncommon phenomenon of metastasis into preexisting intracranial lesions. It should therefore be considered as a differential diagnosis in patients with history of systemic cancer who present with progression of preexistent intracranial lesions.

References

Apr 1, 1977·Southern Medical Journal·T D Weems, J H Garcia
Jan 1, 1978·Acta neurochirurgica·D T Hope, L Symon
Jan 1, 1975·Virchows Archiv. A, Pathological Anatomy and Histology·L Döring
Jul 1, 1975·Journal of Neurology, Neurosurgery, and Psychiatry·A D Hockley
Apr 1, 1976·Southern Medical Journal·E Gyori
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·P ConstantinidesS Jue
Oct 1, 1988·Surgical Neurology·K D PostA G Kandji
Sep 1, 1988·Experimental and Clinical Endocrinology·J A RamsayM H Weiss
Jan 1, 1973·Oncology·K Kovacs
May 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·R Pamphlett
Jan 1, 1984·Virchows Archiv. A, Pathological Anatomy and Histopathology·H P Schmitt
May 1, 1983·Journal of Neurosurgery·R A BernsteinN Wetzel
Apr 1, 1981·Cancer·T W SmithW C Schoene
Jan 1, 1981·Acta neurochirurgica·V M JoglekarC G Blakeney
Jan 1, 1994·Neurosurgical Review·L CervoniR Delfini
May 1, 1994·Australasian Radiology·R BreadmoreM Gonzales
Jul 10, 1999·Pathology·A WongS Halcrow
Nov 9, 2000·Journal of Korean Medical Science·H S HanY C Chu
Dec 18, 2001·Annals of Diagnostic Pathology·C NogaM Mayberg
Apr 3, 2002·British Journal of Neurosurgery·G CserniA Cs Kiss
Nov 29, 2002·Zentralblatt für Neurochirurgie·F MaiuriG D'Acunzi
May 1, 1957·Journal of Neurosurgery·D H OSTERBERG
Aug 1, 1959·Archives of Neurology·J B WALLACH, S EDBERG
Dec 1, 1962·Journal of Neurosurgery·T W WONG, J L BENNINGTON

❮ Previous
Next ❯

Citations

Oct 27, 2010·Surgical Neurology International·Nunung Nur RahmahKazuhiro Hongo
Aug 28, 2016·Neuropathology and Applied Neurobiology·J ShapeyN Kitchen
Jul 3, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Raffaele LongoGiovanna Lanzi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Adhesion Molecules in the Brain

Cell adhesion molecules found on cell surface help cells bind with other cells or the extracellular matrix to maintain structure and function. Here is the latest research on their role in the brain.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Adenocarcinoma, Clear Cell

Clear Cell Adenocarcinoma is a tumor that arises in the female genital tract and is characterized by cells that appear clear under the microscope. Discover the latest research here.

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.

Cavernous Hemangioma

Cavernous hemangioma is a blood vessel defect or benign tumor that leads to leakage of blood to the surrounding tissues. This can occur in several organs including the brain, which can lead to seizures. Discover the latest research on cavernous hemangiomas here.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Related Papers

The Journal of Tropical Medicine and Hygiene
B P Badhe, S Y Sane
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
B DarwishN Smith
© 2021 Meta ULC. All rights reserved