An unusual finding in a desmoid-type fibromatosis of the pancreas: a case report and review of the literature

Journal of Medical Case Reports
Joseph Clarence Torres, Chen Xin

Abstract

Desmoid-type fibromatoses are rare benign and fibrous tumors that account for approximately 0.03% of total neoplasms. Within this category of neoplasms, pancreatic desmoid-type fibromatosis is an extremely rare subgroup, accounting for approximately 5% of desmoid-type fibromatoses. Although the etiology is unknown, some risk factors include trauma, surgery, family history of desmoid tumor, pregnancy, use of contraceptives, genetic mutation, and familial adenomatous polyposis or Gardner syndrome. Desmoid-type tumors are primarily diagnosed by pathological and immunohistochemical studies. The treatment of choice is surgical resection of the tumor. Systemic chemotherapy and radiotherapy are optional treatment approaches for patients with high risk for surgery. The following is a report of an unusual case of a pancreatic desmoid-type fibromatosis in which a very rare variation in the immunohistochemistry findings was demonstrated: slides were immunopositive for S100 protein and not immunonegative. Most desmoid tumors are immunonegative for S100 protein with just a few cases being positive for this protein. We describe the case of a 15-year-old boy, a Chinese national, who was diagnosed as having a pancreatic desmoid-type fibromatos...Continue Reading

References

Aug 28, 2007·Surgical Oncology·George H SakorafasGeorge Peros
Feb 23, 2010·Diseases of the Colon and Rectum·Myles JoyceJames Church
Jan 13, 2011·Arquivos De Gastroenterologia·Raquel Franco LealCláudio Saddy Rodrigues Coy
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Jan 1, 2014·World Journal of Gastroenterology : WJG·Bin XuJun-Jun Ni
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May 7, 2015·Journal of Medical Case Reports·Żaneta Słowik-MoczydłowskaAndrzej Kamiński
Jul 29, 2015·International Journal of Surgical Pathology·Roxana GerlemanSönke Detlefsen
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Methods Mentioned

BETA
SMA
surgical resection

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