Abstract
Desmoid-type fibromatoses are rare benign and fibrous tumors that account for approximately 0.03% of total neoplasms. Within this category of neoplasms, pancreatic desmoid-type fibromatosis is an extremely rare subgroup, accounting for approximately 5% of desmoid-type fibromatoses. Although the etiology is unknown, some risk factors include trauma, surgery, family history of desmoid tumor, pregnancy, use of contraceptives, genetic mutation, and familial adenomatous polyposis or Gardner syndrome. Desmoid-type tumors are primarily diagnosed by pathological and immunohistochemical studies. The treatment of choice is surgical resection of the tumor. Systemic chemotherapy and radiotherapy are optional treatment approaches for patients with high risk for surgery. The following is a report of an unusual case of a pancreatic desmoid-type fibromatosis in which a very rare variation in the immunohistochemistry findings was demonstrated: slides were immunopositive for S100 protein and not immunonegative. Most desmoid tumors are immunonegative for S100 protein with just a few cases being positive for this protein. We describe the case of a 15-year-old boy, a Chinese national, who was diagnosed as having a pancreatic desmoid-type fibromatos...Continue Reading
References
Nov 16, 2004·Gut·N J H SturtR K S Phillips
Aug 28, 2007·Surgical Oncology·George H SakorafasGeorge Peros
Feb 23, 2010·Diseases of the Colon and Rectum·Myles JoyceJames Church
Jan 13, 2011·Arquivos De Gastroenterologia·Raquel Franco LealCláudio Saddy Rodrigues Coy
Apr 12, 2011·The Oncologist·Bernd KasperPeter Hohenberger
Jan 1, 2014·World Journal of Gastroenterology : WJG·Bin XuJun-Jun Ni
Apr 20, 2014·Pancreas·Joo Young KimSeung-Mo Hong
Apr 24, 2014·World Journal of Surgical Oncology·Changjun JiaFeng Xu
May 7, 2015·Journal of Medical Case Reports·Żaneta Słowik-MoczydłowskaAndrzej Kamiński
Jul 29, 2015·International Journal of Surgical Pathology·Roxana GerlemanSönke Detlefsen
Feb 26, 2016·Pathology, Research and Practice·Yoshitane TsukamotoSeiichi Hirota
Mar 15, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Nicolas PenelJean-Yves Blay
Jul 28, 2016·World Journal of Surgical Oncology·Yu-Chieh Wang, Jia-Uei Wong
Nov 29, 2016·Journal of Clinical and Diagnostic Research : JCDR·Marco SantosMarisa Santos
Nov 30, 2016·Oncology Letters·Hongkai ZhangJie Chen
Citations
Dec 18, 2018·Annals of Plastic Surgery·Yuan ChenYong Liu
Dec 17, 2019·Internal Medicine·Masaki TakinamiHiroyuki Ono
Apr 26, 2020·Medicine·Jianchun Xiao, Wenzhe Zhou
Jul 14, 2020·Dermatologic Therapy·Ayşe Serap KaradağKorhan Özkan
Aug 29, 2020·Diagnostic Cytopathology·Andrew B StoneKhalid Amin
Sep 26, 2020·Dermatologic Therapy·Xiao Feng HanLin Ma
Sep 19, 2020·Radiology Case Reports·Shahab ShayestehElliot K Fishman