An unusual sellar mass--solitary plasmacytoma.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
K A MandagereP S Bhatia

Abstract

To describe a case of solitary intrasellar plasmacytoma in a patient with a preoperative diagnosis of a nonfunctioning pituitary adenoma. A case of a solitary intrasellar plasmacytoma is presented, in which the clinical and laboratory findings are detailed and the response to treatment is discussed. Pertinent reports from the literature are reviewed. A 53-year-old woman came to the neurology clinic with complaints of frontal headaches and intermittent blurry vision. Physical examination showed no remarkable findings. Computed tomography revealed an enhancing sellar and suprasellar mass, with extension into the sphenoid and cavernous sinuses. The patient had a preoperative diagnosis of a clinically nonfunctioning pituitary adenoma and underwent transsphenoidal resection. The biopsy specimen was heavily infiltrated with abnormal plasma cells, which stained exclusively for lambda light chain immunoglobulins. An extensive investigation failed to show evidence of multiple myeloma. In view of these findings, the diagnosis of solitary extramedullary plasmacytoma was made. Postoperatively, the patient received radiotherapy to the pituitary and has remained free of disease for 7 years. Review of the world literature disclosed only 17 pr...Continue Reading

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Citations

Oct 12, 2011·Pituitary·Rene Joukhadar, Ken Chiu
Aug 30, 2008·Acta neurochirurgica·E YamanS Buyukberber
Nov 25, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Imad Saeed KhanAnil Nanda
Feb 16, 2012·Diagnostic Cytopathology·Negar AzarpiraAlireza Rasekhi
Mar 5, 2008·Journal of Neuro-oncology·Vincenzo PitiniGiuseppe Altavilla

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