An update on biological therapies for pediatric allergic diseases.

Minerva pediatrica
Giorgio CiprandiAmelia Licari

Abstract

Allergic diseases represent a global health burden. Patients with allergic diseases may experience disability, reduced quality of life and productivity, emotional distress, and social restrictions, especially in the most severe cases. Current advances in unveiling the pathogenesis of allergic disorders have paved the way for the development of novel therapeutic strategies. Biological drugs have been widely studied in pediatric allergic asthma, with strong evidence of efficacy and safety. Moreover, promising results derive from studies on other conditions such as atopic dermatitis, chronic spontaneous urticaria, and food allergy. This review analyzes recent evidence on the role of biologic therapies for allergic diseases, focusing on the pediatric age.

References

Nov 17, 2009·The Journal of Allergy and Clinical Immunology·Bob LanierCarlos Fernandez Vidaurre
Mar 18, 2011·The New England Journal of Medicine·William W BusseChristine A Sorkness
May 7, 2011·The Journal of Allergy and Clinical Immunology·Kari C NadeauDale T Umetsu
Jun 12, 2012·Archives of Disease in Childhood·Malcolm BrodlieDavid A Spencer
Feb 26, 2013·The New England Journal of Medicine·Marcus MaurerThomas Casale
Mar 23, 2013·The European Respiratory Journal·Antoine DeschildreJocelyne Just
Nov 2, 2013·The Journal of Allergy and Clinical Immunology·Lynda C SchneiderDale T Umetsu
Jan 7, 2014·The Journal of Allergy and Clinical Immunology·Scott H Sicherer, Hugh A Sampson
Mar 1, 2014·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Philippe BéginKari C Nadeau
Jul 10, 2014·The New England Journal of Medicine·Lisa A BeckAllen R Radin
Nov 19, 2014·Paediatric Drugs·Amelia LicariGian Luigi Marseglia
May 17, 2015·Expert Opinion on Drug Discovery·Amelia LicariGiorgio Ciprandi
May 30, 2015·The European Respiratory Journal·Antoine DeschildreJocelyne Just
Nov 1, 2015·The Journal of Allergy and Clinical Immunology·Stephen J TeachStanley J Szefler
Mar 24, 2016·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·C Martorell-CalatayudM D De Las Marinas-Álvarez
Oct 4, 2016·The New England Journal of Medicine·Eric L SimpsonUNKNOWN SOLO 1 and SOLO 2 Investigators
Apr 5, 2017·Current Opinion in Allergy and Clinical Immunology·Alessandro FiocchiMaurizio Mennini
May 10, 2017·The Journal of Allergy and Clinical Immunology·Bradley E ChippsWilliam W Busse
Oct 28, 2017·Expert Opinion on Drug Discovery·Amelia LicariGiorgio Ciprandi
Nov 28, 2017·The Journal of Allergy and Clinical Immunology. in Practice·Matthew D StraesserMonica G Lawrence
Dec 8, 2017·Current Respiratory Medicine Reviews·Amelia LicariUNKNOWN Omalizumab in Childhood Asthma Italian Study Group
Dec 16, 2017·The Lancet. Gastroenterology & Hepatology·Sandra AndorfR Sharon Chinthrajah
Jan 2, 2018·Current Respiratory Medicine Reviews·Amelia LicariGian Luigi Marseglia
Jan 18, 2018·Allergy·T ZuberbierUNKNOWN Endorsed by the following societies: AAAAI, AAD, AAIITO, ACAAI, AEDV, APAAACI, ASBAI, ASCIA, BAD, BSACI, CDA, CMICA, CSACI,
Apr 18, 2018·Journal of Asthma and Allergy·Farnaz Tabatabaian, Dennis K Ledford
May 11, 2018·The World Allergy Organization Journal·Mario Sánchez-BorgesLanny Rosenwasser
Jun 8, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·A WollenbergUNKNOWN European Dermatology Forum (EDF), the European Academy of Dermatology and Venereology (EADV), the European Academy of Allerg
Jul 5, 2018·Frontiers in Pediatrics·Amelia LicariGian L Marseglia
Oct 5, 2018·Pediatric Allergy, Immunology, and Pulmonology·Elissa M AbramsStanley J Szefler
May 6, 2019·Medicina·Amelia LicariGian Luigi Marseglia
Jul 22, 2019·Paediatric Drugs·Amelia LicariGian Luigi Marseglia
Jul 30, 2019·Frontiers in Pediatrics·Amelia LicariGian Luigi Marseglia
Aug 17, 2019·Italian Journal of Pediatrics·Carlo CaffarelliFabio Cardinale
Aug 20, 2019·The Journal of Allergy and Clinical Immunology·Atul GuptaJonathan Steinfeld
Sep 11, 2019·Pediatric Pulmonology·Atul GuptaSteven W Yancey
Oct 14, 2019·Journal of the American Academy of Dermatology·Sean IgelmanElaine Siegfried
Oct 30, 2019·Current Pediatric Reviews·Amelia LicariGian Luigi Marseglia
Feb 14, 2020·Expert Opinion on Biological Therapy·Amelia LicariGiorgio Ciprandi
Feb 29, 2020·Minerva pediatrica·Riccardo CastagnoliAmelia Licari
Mar 12, 2020·Paediatric Drugs·Amelia LicariGian Luigi Marseglia

❮ Previous
Next ❯

Citations

Aug 1, 2020·Minerva pediatrica·Riccardo CastagnoliGian Luigi Marseglia
Jun 1, 2021·Expert Review of Respiratory Medicine·Maria De FilippoGian Luigi Marseglia

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Current Pediatric Reviews
Amelia LicariGian Luigi Marseglia
Current Gene Therapy
Ya-Hui ChuangBor-Luen Chiang
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Alyssa A OlandBruce G Bender
© 2021 Meta ULC. All rights reserved