An update on cirrhotic cardiomyopathy

Expert Review of Gastroenterology & Hepatology
S MøllerF Bendtsen

Abstract

Cirrhosis with portal hypertension and related complications are associated with a high mortality. Excess of circulating vasodilators and cardiodepressive substances lead to a hyperdynamic circulation with changed myocardial structure and function. The entity cirrhotic cardiomyopathy seems to be involved in different aspects of hepatic decompensation, which focuses on new targets of treatment. Areas covered: This review deals with contemporary aspects of cirrhotic cardiomyopathy, and the literature search was undertaken by PubMed with 'cirrhotic' and 'cardiomyopathies' as MeSH Terms. Cirrhotic cardiomyopathy is defined as the presence of systolic and diastolic dysfunction and electrophysiological abnormalities. The diagnosis is based on contemporary Doppler/Echocardiography measurements or quantitative magnetic resonance imaging. Cirrhotic cardiomyopathy is independent of the etiology of the liver disease but related to severity and survival. Expert commentary: The outcome of invasive procedures and liver transplantation is influenced by the presence of cardiac dysfunction. Therefore, a cautious cardiac evaluation should be included in the patient evaluation prior to liver transplantation. Liver transplantation ameliorates most...Continue Reading

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Citations

Apr 5, 2020·Journal of Cardiovascular Translational Research·Sérgio Luiz Borges de SouzaAndré Ferreira do Nascimento
Jan 14, 2021·Journal of Intensive Care Medicine·Madhumita PremkumarSmita Divyaveer
Apr 27, 2020·Best Practice & Research. Clinical Anaesthesiology·Andrea De GasperiGianni Biancofiore
Nov 23, 2020·Archives of Medical Research·Cristina Schmitt GregolinAndré Ferreira do Nascimento
Aug 21, 2021·Deutsche medizinische Wochenschrift·Philipp KasperGuido Michels

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